Research location: Toronto General Hospital/Research Institute (UHN)
Primary Research Area: Cardiovascular
Secondary Research Area: Molecular & Cell Biology
1. The functions of resident CD11c+ myeloid cells in healthy mouse aorta and in the initiation of atherosclerosis. 2. The role of oxidized lipid loading on TLR-induced inflammatory gene expression in primary macrophages and dendritic cells. 3. Mechanisms regulating basal NF-kappaB homeostasis in endothelial cells.