Faculty Research Database

This is a database for faculty who have submitted a research profile. To view all LMP faculty and their contact information, go to the Faculty Contact Directory.

B

Hal Berman
MD, PhD
Assistant Professor
Research Location: Toronto General Hospital/Research Institute (UHN)
Primary Research Area: Cancer
Secondary Research Area: Molecular & Cell Biology

My laboratory investigates the basic cellular pathways and processes that maintain proper growth and differentiation in tissues under the control of sex hormones.  We develop vitro models originating from normal primary human cells derived from patient biopsies to address basic questions in both breast and ovarian carcinogenesis.

Phone: 416-340-4607
MD
Associate Professor
Research Location: Toronto General Hospital/Research Institute (UHN)
Primary Research Area: Cardiovascular
Secondary Research Area: Infectious Diseases & Immunopathology
Phone: 416-340-3706
Joan Boggs
BA, MSc, PhD
Professor Emeritus / Emerita
Research Location: The Hospital for Sick Children/Research Institute
Primary Research Area: Brain & Neuroscience
Secondary Research Area: Molecular & Cell Biology

My research program is aimed at understanding myelinogenesis by oligodendrocytes. We are currently focusing on the structure and roles of myelin basic protein in interactions with the cytoskeleton and SH3-domain proteins and the role of glycosphingolipids in cell-surface phenomena. We are also studying the effect of estrogens on oligodendrocytes and myelin.

Phone: 416-813-5919
PhD
Associate Professor
Research Location: University of Toronto - St. George Campus (downtown)
Primary Research Area: Molecular & Cell Biology
Phone: 416-978-5854
Shelley Boyd
BSc, MD, FRCS(C)
Assistant Professor
Research Location: St. Michael's Hospital/Research Institute
Primary Research Area: Brain & Neuroscience
Secondary Research Area: Human Development & Aging

Our team focuses on the mechanisms and potential treatments of blinding eye disease.  We take a fully integrated translational approach that includes pre-clinical models of disease, biomarker development, and early and late phase clinical trial. 

Phone: 416-864-6060
Ext: 2893
PhD
Lecturer
Research Location: Toronto General Hospital/Research Institute (UHN)
Phone: 416-340-4800
Ext: 5676
PhD
Associate Professor
Research Location: Other (e.g. government, industry, etc.)
Primary Research Area: Hematopathology
Secondary Research Area: Infectious Diseases & Immunopathology

Main research: (1) The mechanism of how IVIG and recombinant Fc multimers ameliorate ITP and RA in mouse models. (2) Studies of recombinant proteins and small molecules to replace high-dose IVIG in patients with autoimmune and inflammatory diseases. (3) Use of a phagocytosis assay to predict the clinical significance of antibodies against red cell blood cells and to select donor blood for transfusion into patients with complex antibody problems.

Phone: 416-313-4458
PhD
Professor
Research Location: Mount Sinai Hospital/Research Institute
Primary Research Area: Cancer
Secondary Research Area: Genetics, Genomics & Proteomics

We study the process by which a mutation in a single cell eventually leads to malignant cancer.  We utilize a variety of techniques that incorporate cutting edge genetics, genomics, and proteomics strategies.

Phone: 647-826-1525
MD, FRCPC
Associate Professor
Research Location: The Hospital for Sick Children/Research Institute
Primary Research Area: Hematopathology
Phone: 416-813-7736
PhD, FCACB
Assistant Professor
Primary Research Area: Genetics, Genomics & Proteomics
Secondary Research Area: Infectious Diseases & Immunopathology

I am interested in projects that aim to discover biomarkers of disease or biomarkers that are informative about the patients’ response to therapy. As part of this effort, the aim is also to develop new methods for possible clinical laboratory applications, such as immuno-mass spectrometry or improved immunoassays, capable of detecting proteins with specific post-translational modifications, isoforms, or activity.

Phone: 416-340-4800
Ext: 7199
Gueorgui (George) Broukhanski
PhD, MS
Assistant Professor
Research Location: Other (e.g. government, industry, etc.)
Primary Research Area: Infectious Diseases & Immunopathology
Secondary Research Area: Genetics, Genomics & Proteomics

Initiates and implements research studies in molecular epidemiology of Clostridium difficile, investigates biomarkers associated with strains causing outbreaks in hospitals, develops methods for detection and typing of this pathogen, supervises implementation of these methods for routine testing at the Public Health Ontario Laboratories.

Phone: 647-792-3427
Martha Brown
BSc, MSc, PhD
Associate Professor
Research Location: University of Toronto - St. George Campus (downtown)
Primary Research Area: Infectious Diseases & Immunopathology
Secondary Research Area: Molecular & Cell Biology

My lab studies the human fastidious enteric adenoviruses (HAdV-40 and 41), with a primary focus on their unique structural features and the role of these features as determinants of gut tropism. Related projects include the development of HAdV-40/41 as vaccine vectors and the study of antiviral agents for treatment of adenovirus infection.    

Phone: 416-978-5853
Jagdish Butany
MBBS, MS, FRCPC
Professor
Research Location: Toronto General Hospital/Research Institute (UHN)
Primary Research Area: Cardiovascular
Phone: 416-340-3003

C

Jeannie Callum
BA, MD, FRCPC, CTBS
Associate Professor
Research Location: Sunnybrook Health Science Centre/Research Institute
Primary Research Area: Hematopathology

My current research areas of focus are in the following areas: (1) Transfusion support in trauma patients; (2) Transfusion support following cardiac surgery; (3) Transfusion triggers in critically ill patients; (4) Adverse reactions to blood products; (5) Transfusion-related process errors; and, (6) Management of peri-pregnancy and perioperative iron deficiency anemia.

Phone: 416-480-4045
PhD, FACMG
Assistant Professor

My research interest includes improvement of traditional molecular genetics approaches and development of novel diagnostic tests, particularly in cancer genetics, using high-throughput technologies like Next-Generation Sequencing. These translational research activities will focus on the following aspects of molecular pathology: (1) Genomic alterations in oncology, (2) High-throughput genotyping in cancer and (3) Methylome analysis.

Phone: 416-340-4800
Ext: 3146
MD, CM, FRCPC
Assistant Professor
Research Location: Sunnybrook Health Science Centre/Research Institute
Phone: 416-480-6100
Ext: 7358
PhD, JD
Adjunct Professor
Phone: 437-836-3089
MSc, PhD, DABCC, FCACB
Assistant Professor
Research Location: Sunnybrook Health Science Centre/Research Institute
Primary Research Area: Cancer
Secondary Research Area: Brain & Neuroscience

My research focuses on two areas: (1) clinical utility of biomarkers (proteins & DNA) in lymphoproliferative and cerebrovascular diseases, and (2) practice-based research;

Phone: 416-480-6100
Ext: 2688
M.B., B.S., M.D., D.M., Ph.D.
Associate Professor
Research Location: Toronto Western Hospital/Research Institute (UHN)
Primary Research Area: Genetics, Genomics & Proteomics
Secondary Research Area: Infectious Diseases & Immunopathology

Dr. Chandran’s research focuses in the identification of psoriatic disease biological markers with the use of transcriptomic, proteomic and metabolomic approaches. His research further aims to identify the mechanisms underlying inflammation, joint damage and pain in psoriatic disease. The ultimate goal of Dr. Chandran’s work is translating these findings into the development of novel therapeutics with the help of bioinformatics and augmented inte

Phone: 416-603-5912
MD, PhD, FRCPC
Professor
Research Location: Toronto General Hospital/Research Institute (UHN)
Primary Research Area: Molecular & Cell Biology
Secondary Research Area: Hematopathology

We are interested in studying the molecular pathogenesis of multiple myeloma (MM) and identifying prognostic and predictive biomarkers in MM. We are also interested in pre-clinical evaluation of small molecules targeting various oncogenic signaling pathways as novel therapeutic strategies in MM.      

Phone: 416-340-4858

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