Faculty Research Database

Click on "Select Profile" below to focus on up to six faculty profiles.

This is a database for faculty who have submitted a research profile. To view all LMP faculty and their contact information, go to the Faculty Contact Directory.

C

MD, PhD, FRCPC
Professor
Research Location: Toronto General Hospital/Research Institute (UHN)
Primary Research Area: Molecular & Cell Biology
Secondary Research Area: Hematopathology

We are interested in studying the molecular pathogenesis of multiple myeloma (MM) and identifying prognostic and predictive biomarkers in MM. We are also interested in pre-clinical evaluation of small molecules targeting various oncogenic signaling pathways as novel therapeutic strategies in MM.      

Phone: 416-340-4858
MD, PhD, FCAP, FRCPC
Associate Professor
Research Location: Mount Sinai Hospital/Research Institute
Primary Research Area: Cancer
Secondary Research Area: Molecular & Cell Biology

My main research interest is in the clinicopathologic and molecular characterization of breast carcinoma. This includes: evaluation of pathologic predictors of recurrence and treatment response, role of host factors in breast cancer progression, and molecular correlates of structural/histologic changes.  Other interests: ovarian cancer, digital pathology.

Phone: 416-586-4800
Ext: 7317
MSc, PhD, FACMG
Assistant Professor
Research Location: Mount Sinai Hospital/Research Institute
Primary Research Area: Genetics, Genomics & Proteomics
Secondary Research Area: Cancer

Dr. Charames' research interests are in the development of genomic and proteomic strategies for improved clinical diagnostics, with a special focus in breast, ovarian and colorectal cancers. His translational research approach aims to use high-throughput genomic sequencing, in addition to proteomics and biomarker discovery technologies, to improve individualized medicine.

Phone: 416-586-4800
Ext: 6115
MBBS, FRCPC
Assistant Professor
Research Location: Credit Valley Hospital
Primary Research Area: Genetics, Genomics & Proteomics

Dr. Chaudhry's research interests include detailed delineation of phenotype of rare genetic disorders. She is also interested in research aimed at finding genetic etiology of craniofacial disorders, autism and intellectual disability.

Phone: 905-813-4104
MD, PhD, JD, FRCPC
Assistant Professor
Research Location: Toronto General Hospital/Research Institute (UHN)
Primary Research Area: Genetics, Genomics & Proteomics
Phone: 416-340-4800
Ext: 5911
MD, FRCPC
Assistant Professor
Research Location: The Hospital for Sick Children/Research Institute
Primary Research Area: Cardiovascular
Phone: 416-813-6848
MD, FABMG, FACMG, FCCMG, FRCPC
Professor
Research Location: Mount Sinai Hospital/Research Institute
Primary Research Area: Genetics, Genomics & Proteomics
Secondary Research Area: Cardiovascular

Current genetic evaluation of stillbirths is based on clinical grounds (autopsy, examination of tissues) and laboratory testing (karyotype, microarray analysis). For 25-65% of stillbirths the etiology cannot be determined by current standard investigations. Our current research is aimed towards finding single gene disorders assocaited with fetal abnormalities by using whole exome sequencing (WES) and in the future whole exome sequencing.

Phone: 416-586-4523
MBBCh, FRCPS (C)
Associate Professor
Research Location: Toronto General Hospital/Research Institute (UHN)
Phone: 416-340-3396
MD, PhD, FRCPC
Assistant Professor
Research Location: Toronto General Hospital/Research Institute (UHN)
Primary Research Area: Infectious Diseases & Immunopathology
Secondary Research Area: Genetics, Genomics & Proteomics

My laboratory interests include the role of the human microbiome in infectious diseases pathogenesis, it's potential as a clinical biomarker in infectious and non-infectious diseases and the interactions of the human microbiome, host and antibiotics during treatment for infection.

Phone: 416-581-7457
PhD, DABCC, FCACB
Assistant Professor
Research Location: The Hospital for Sick Children/Research Institute
Primary Research Area: Metabolism & Nutrition

My research interest focuses on pharmacokinetics and therapeutic drug monitoring/toxicology with application towards investigating the expression of drugs into breast milk and the risk these drugs may pose to the nursing infant.  

Phone: 416-813-6817
MD, PhD, FRCPC, FCCMG
Professor
Research Location: Sunnybrook Health Science Centre/Research Institute
Primary Research Area: Genetics, Genomics & Proteomics
Secondary Research Area: Metabolism & Nutrition

Our research interests include a wide range of genetic conditions, but our laboratory has a specific focus on genetic and non-genetic contributions to disordered bone and mineral metabolism. 

Phone: 416-480-6100
BA, PhD
Professor
Research Location: St. Michael's Hospital/Research Institute
Primary Research Area: Metabolism & Nutrition
Secondary Research Area: Cardiovascular

Biomarker investigation in subjects with or at risk for diabetes and renal disease.  Basic mechanisms of the lactonase, paraoxonase 1 in atherosclerosis and inflammation. 

Phone: 416-864-6023
MSc, MD(Cantab), MRCP, FFPH
Professor
Research Location: Other (e.g. government, industry, etc.)
Primary Research Area: Infectious Diseases & Immunopathology

As a public health physician my most significant research involves epidemiological studies designed to answer applied public health questions for decision-makers on infectious diseases and immunization. Outcomes include changes in policy and practice. Research funding has been for research of national and global significance.     

Phone: 647-260-7401
MD, FRCPC
Assistant Professor
Research Location: Toronto General Hospital/Research Institute (UHN)
Primary Research Area: Hematopathology
Secondary Research Area: Genetics, Genomics & Proteomics

Research and education focus on transfusion medicine and benign hematology (ie- adverse reactions to blood products; immunologic hematopathologies in autoimmune disease, transfusion, or transplantation; and adaptive/evolutionary blood group biology).

Phone: 416-340-5390
MD, FRCPC
Professor Emeritus / Emerita
Research Location: The Hospital for Sick Children/Research Institute
Primary Research Area: Cardiovascular
Secondary Research Area: Molecular & Cell Biology

In the basic science sphere our studies focus on the role and function of pulmonary neuroendocrine cells particularly their cellular and molecular mechanisms of O2 /CO2 sensing ; in the clinical research our studies focus on molecular mechanisms of congenital enteropathies,disorders of surfactant metabolism and  novel forms of cardiomyopathies

Phone: 416-813-5996
MD
Professor
Research Location: Toronto General Hospital/Research Institute (UHN)
Primary Research Area: Cardiovascular
Secondary Research Area: Molecular & Cell Biology

Our research focuses on initiation of atherosclerosis, specifically regional differences in the normal arterial intima that predispose it to atherogenesis, intimal dendritic cells and monocyte recruitment and myeloid cell proliferation in early lesions.  Another focus is functions of alpha-4 integrins in leukocyte recruitment to sites of inflammation.

Phone: 416-581-7483

D

PhD
Associate Professor
Research Location: Sunnybrook Health Science Centre/Research Institute
Primary Research Area: Molecular & Cell Biology
Secondary Research Area: Brain & Neuroscience

Our research program focuses on discovering and elucidating the molecular signaling pathways and transcription factors responsible for the development of the mechanosensory hair cells - cells that detect sound, and auditory neurons - cells that transmit sound information from the hair cells to the brain, in the mammalian inner ear.  

Phone: 416-480-6804
MD, PhD
Assistant Professor
Research Location: St. Michael's Hospital/Research Institute
Primary Research Area: Cancer
Secondary Research Area: Brain & Neuroscience

Our lab is interested in the mechanisms that underlie the stem cell identity and direct cell fate in the normal brain and in glioblastoma.       

Phone: 416-864-5548
MD, PhD
Professor
Research Location: Toronto General Hospital/Research Institute (UHN)
Primary Research Area: Hematopathology
Secondary Research Area: Molecular & Cell Biology

Lymphoma research interests
1. diagnostics, biology and immunology of lymphoma.
2. pathology review for trials 

Phone: 416-340-4800
Ext: 5239
PhD
Professor
Research Location: Mount Sinai Hospital/Research Institute
Primary Research Area: Cancer
Secondary Research Area: Molecular & Cell Biology

Dr. Dennis has been studying metastasis for decades. One of his current projects focuses on cancer cell metabolism, and how cancer cells consume more energy, grow aberrantly, and spread throughout the body.

Phone: 416-586-8233

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