Faculty Research Database

Click on "Select Profile" below to focus on up to six faculty profiles.

This is a database for faculty who have submitted a research profile. To view all LMP faculty and their contact information, go to the Faculty Contact Directory.

L

BSc, MSc, MD, FRCP(C)
Associate Professor
Phone: 416-864-5858
PhD
Professor
Research Location: St. Michael's Hospital/Research Institute
Primary Research Area: Infectious Diseases & Immunopathology
Secondary Research Area: Hematopathology

Understanding how therapeutic antibodies can be used to treat autoimmune disease. We study the ability of novel monoclonal antibodies, as well as antibodies taken from the plasma of healthy blood donors (IVIg) to inhibit disease progression in autoimmunity. We also study how an antibody called "anti-D" is able to prevent haemolytic disease of the fetus and newborn.

Phone: 416-864-5599
PhD
Associate Professor
Research Location: University of Toronto - St. George Campus (downtown)
Primary Research Area: Infectious Diseases & Immunopathology
Secondary Research Area: Molecular & Cell Biology

Our laboratory is interested in understanding the molecular mechanisms at play in the tug-of-war between viruses and the host. We want to understand how certain retroviruses enter cells and are then antagonized by innate immune molecules. Immunological recognition and restriction of viral pathogens is fundamental for fighting infectious disease.

Phone: 416-978-1060
MD, FRCPC, PhD
Associate Professor
Research Location: St. Michael's Hospital/Research Institute
Primary Research Area: Cardiovascular
Secondary Research Area: Infectious Diseases & Immunopathology

My lab has an interest in how microvascular endothelial permeability is controlled. A number of projects examine how the host-pathogen interaction affects endothelial permeability.  In addition, we are investigating how the movement of critical proteins and hormones across the endothelium is regulated.

Phone: 416-864-6060
Ext: 77655
PhD, FACMG
Assistant Professor
Research Location: Mount Sinai Hospital/Research Institute
Primary Research Area: Genetics, Genomics & Proteomics
Secondary Research Area: Cancer

Dr Lerner-Ellis is a molecular geneticist who serves as Head and Director of the Advanced Molecular Diagnostics Laboratory at Mount Sinai Hospital and an Associate at the Ontario Institute for Cancer Research.  In addition to his core interests in molecular diagnostics, as applied to breast and colon cancer, a major aim of his research is to integrate genome sequencing into the general practice of medicine.     

Phone: 416-586-4800
Ext: 6115
MBBS
Lecturer
Research Location: North York General Hospital
Primary Research Area: Cancer
Phone: 416-756-6252
MD, FRCPC
Professor
Research Location: Toronto General Hospital/Research Institute (UHN)
Primary Research Area: Molecular & Cell Biology

We have identified the molecules tissue factor and fgl2/fibroleukin, which are membrane associated serine proteases. These molecules play pivotal roles in the pathogenesis of viral hepatitis (fgl2/fibroleukin), allo- and xenograft rejection (tissue factor and fgl2).

Phone: 416-340-5166
MD, PhD
Professor
Research Location: Toronto General Hospital/Research Institute (UHN)
Primary Research Area: Cardiovascular
Secondary Research Area: Molecular & Cell Biology

Ren-Ke Li’s research focuses on translational research to apply new insights discovered through basic science research to clinical applications for heart regeneration and repair after myocardial infarction. Research areas are: 1) Cell transplantation into damaged tissue to regenerate myocardium and restore heart function. 2) Tissue engineering to create a muscle graft using stem cells and biomaterials for repair of cardiac defects.

Phone: 416-581-7492
Bach of Medicine, PhD, FRCPC
Lecturer
Phone: 905-472-7000
Ext: 6691
MD, FRCP(C), FASN
Professor
Research Location: The Hospital for Sick Children/Research Institute
Primary Research Area: Molecular & Cell Biology
Secondary Research Area: Genetics, Genomics & Proteomics

Complement-based kidney diseases and the translational aspects involved through clinical and basic reseach    

Phone: 416-813-7654
Ext: 309343
BA, MD, FRCPC
Assistant Professor
Primary Research Area: Hematopathology

Research and education focus on transfusion medicine and benign hematology with a special interest in pediatric transfusion issues.  

Phone: 416-340-5390
MD, FRCPC
Associate Professor
Research Location: Sunnybrook Health Science Centre/Research Institute
Primary Research Area: Hematopathology

My research interests are in the appropriate use of blood transfusion and improving physician education in transfusion medicine.     

Phone: 416-480-6100
Ext: 2781
PhD
Professor
Research Location: The Hospital for Sick Children/Research Institute
Primary Research Area: Infectious Diseases & Immunopathology
Secondary Research Area: Metabolism & Nutrition

Our laboratory studies the functional role of glycosphingolipids in cell physiology and disease pathology. Abnormal GSL metabolism is associated with many human diseases and major aspects of their metabolism remain undefined.          

Phone: 416-813-5998
MD, FRCPC
Assistant Professor
Research Location: Sunnybrook Health Science Centre/Research Institute
Primary Research Area: Cancer
Secondary Research Area: Genetics, Genomics & Proteomics

Breast and gynecologic cancer research

Phone: 416-480-4279

M

MD, MBA
Associate Professor
Phone: 416-756-6517
MD, FRCPC
Assistant Professor
Research Location: Mount Sinai Hospital/Research Institute
Primary Research Area: Cancer
Phone: 416-586-1575
DDS, MSc, PhD, FRCDC
Assistant Professor
Research Location: University of Toronto - St. George Campus (downtown)
Primary Research Area: Cancer
Secondary Research Area: Molecular & Cell Biology

The Cancer Invasion and Metastasis laboratory (CIMlab) uses a combination of cell biology, leading edge imaging techniques and clinical studies to investigate the mechanisms of early cancer invasion.    

Phone: 416-979-4920
Ext: 4485
PhD
Assistant Professor
Research Location: Other (e.g. government, industry, etc.)
Primary Research Area: Infectious Diseases & Immunopathology
Secondary Research Area: Molecular & Cell Biology

My current interest is in microbiology of foodborne pathogens. Particularly, I focus on Listeria to investigate the mechanisms activated by Listeria monocytogenes to sense the transit between different environments (saprophyte versus invasive).

Furthermore I am implicated in projects to improve microorganisms detection and typing by molecular methods as part of an outbreak response.

Phone: 647-792-3428
MD
Professor
Research Location: St. Michael's Hospital/Research Institute
Primary Research Area: Molecular & Cell Biology

I have a research program in the field of cellular and molecular regulation of endothelial gene expression. The lab is focused on understanding the contribution of endothelial cells to human health and disease. We are especially motivated towards understanding the contribution of important endothelial genes to disease processes and novel aspects of how endothelial genes are regulated.

Phone: 416-847-1736
PhD
Assistant Professor
Research Location: The Hospital for Sick Children/Research Institute
Primary Research Area: Genetics, Genomics & Proteomics
Secondary Research Area: Molecular & Cell Biology

My research is focused on using high throughput genomic technologies, including microarrays and sequencing, for gene discovery and diagnostics in neurodevelopmental disorders.  

Phone: 416-813-7654
Ext: 306015

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