Faculty Research Database

Click on "Select Profile" below to focus on up to six faculty profiles.

This is a database for faculty who have submitted a research profile. To view all LMP faculty and their contact information, go to the Faculty Contact Directory.

M

MD, FRCPC
Assistant Professor
Research Location: St. Michael's Hospital/Research Institute
Primary Research Area: Infectious Diseases & Immunopathology
Secondary Research Area: Molecular & Cell Biology
Phone: 416-864-6060
Ext: 2946
MD, FRCPC, FACP
Professor
Research Location: Mount Sinai Hospital/Research Institute
Primary Research Area: Infectious Diseases & Immunopathology
Secondary Research Area: Molecular & Cell Biology

My research interests include clinical development, evaluation, and utility of viral diagnostic testing as well as rapid diagnostic testing.  I am also involved in research related to the epidemiology of antibiotic resistance in the community particularly as it relates to organisms associated with infections of the respiratory tract and urinary tract.         

Phone: 416-586-4695
BSc, DDS, PhD, FRCD(C)
Professor
Research Location: University of Toronto - St. George Campus (downtown)
Primary Research Area: Molecular & Cell Biology
Secondary Research Area: Cardiovascular

Dr. McCulloch has defined critical signaling systems that regulate periodontal and cardiac connective tissues. The ultimate goal of his research is to define new therapies for periodontal and cardiovascular disorders. Since 2006, Dr. McCulloch has trained >50 undergraduate and graduate students, and generated over 70 peer-reviewed publications, has two patent applications and has won several major scientific awards.

Phone: 416-978-1258
MSc, MD, FRCPC
Professor
Research Location: Mount Sinai Hospital/Research Institute
Primary Research Area: Infectious Diseases & Immunopathology
Secondary Research Area: Human Development & Aging

Dr. McGeer primary areas of research interest are the prevention of healthcare associated infection, antimicrobial resistance, the epidemiology of influenza, and adult immunization.

Phone: 416-586-3118
DVM, DVSc, MRCVS
Professor
Research Location: The Hospital for Sick Children/Research Institute
Primary Research Area: Genetics, Genomics & Proteomics

I’m focused on discovering and understanding the function of genes and abnormalities in genes (“mutations”) that cause disease in children and adults. My pathology lab studies tissue changes associated with mutations. My molecular biology lab focuses on R&D in design and production of mutant mouse models, particularly Cas9 RNA-guided nucleases, germ cell cryopreservation, and in vitro fertilization.

Phone: 647-837-5840
PhD
Professor
Research Location: Sunnybrook Health Science Centre/Research Institute
Primary Research Area: Brain & Neuroscience
Secondary Research Area: Human Development & Aging

My research focuses on development of therapeutics to target protein-misfolding disorders, in particular Alzheimer’s disease. Stemming from the basic research of protein-lipid interactions, we identified a family of compounds that inhibit the formation of toxic soluble aggregates in Alzheimer’s disease that has added to our understanding of disease progression and human clinical trials. 

Phone: 416-480-6100
Ext: 7720
Karim Mekhail
PhD
Associate Professor
Research Location: University of Toronto - St. George Campus (downtown)
Primary Research Area: Molecular & Cell Biology
Secondary Research Area: Human Development & Aging

The ultimate goal of our research group is to chart molecular networks dictating the non-random distribution of DNA in the nucleus and understand how this order maintains genome stability and human health.

Phone: 416-946-8132
MSc, PhD
Assistant Professor
Research Location: Other (e.g. government, industry, etc.)
Primary Research Area: Infectious Diseases & Immunopathology
Secondary Research Area: Genetics, Genomics & Proteomics

My lab is involved in the detection and characterization of resistance mechanisms to different antibiotic families in both Gram-negative and -positive pathogens. Elucidation of genetic platforms and enzymatic activity are part of that molecular characterization. Development of genetic and phenotypic tests is also part of our work through new technologies applied to diagnosis.

Phone: 647-792-3430
MD, FRCPC
Associate Professor
Research Location: Toronto General Hospital/Research Institute (UHN)
Primary Research Area: Cancer
Secondary Research Area: Genetics, Genomics & Proteomics

Dr. Mete’s research focusses on the translation of basic findings to clinical tests that provide diagnostic, prognostic, and predictive biomarkers for endocrine tumors. His other interests involve development of practice guidelines, digital pathology, and innovative teaching designs.

Phone: 416-340-3004
BSc(HON), MSc, PhD, MBA
Professor Emeritus / Emerita
Primary Research Area: Cardiovascular
Secondary Research Area: Infectious Diseases & Immunopathology
PhD
Associate Professor
Research Location: University of Toronto - St. George Campus (downtown)
Primary Research Area: Molecular & Cell Biology
Secondary Research Area: Infectious Diseases & Immunopathology

We study how the NLRP1 inflammasome detects the metabolic stress that is caused by infections.  We are also investigating the entry mechanism of anthrax toxin.

Phone: 416-946-8095
MD, PhD
Assistant Professor
Research Location: The Hospital for Sick Children/Research Institute
Primary Research Area: Infectious Diseases & Immunopathology
Secondary Research Area: Molecular & Cell Biology

The overall research goal of the lab is to reduce the burden of disease caused by viral inflammation in the lung with a focus on Respiratory Syncytial Virus (RSV).   The lab has expertise in airway epithelial cell biology and uses airway cell model systems to study a few lung diseases, most notably Cystic Fibrosis.    

Phone: 416-813-2196
MD, MPH, FRCPC
Assistant Professor
Research Location: Mount Sinai Hospital/Research Institute
Primary Research Area: Human Development & Aging
Secondary Research Area: Genetics, Genomics & Proteomics

Dr. Morgen's research focuses on pathologic and laboratory predictors of fetal, obstetrical, and neonatal complications, and as such he collaborates extensively with obstetricians and neonatologists.

Phone: 416-586-4457
BA, BSc, PhD
Assistant Professor
Research Location: University of Toronto - St. George Campus (downtown)
Primary Research Area: Infectious Diseases & Immunopathology
Secondary Research Area: Molecular & Cell Biology

Blood-borne dissemination of pathogens is responsible for most of the mortality associated with bacterial infections, but dissemination mechanisms remain largely uncharacterized. We investigate the dissemination mechanisms of invasive bacteria (especially the Lyme disease spirochete Borrelia burgdorferi), in an effort to develop alternative therapeutic approaches for treating bacterial infection.

Phone: 416-978-6685
MD, FRCPC
Assistant Professor
Research Location: Sunnybrook Health Science Centre/Research Institute
Primary Research Area: Infectious Diseases & Immunopathology

The focus of our research program is on virus transmission between hosts with an emphasis on the aerobiology of influenza virus.        

Phone: 416-480-4823
MD, FRCPC
Associate Professor
Research Location: Mount Sinai Hospital/Research Institute
Primary Research Area: Cancer
Secondary Research Area: Molecular & Cell Biology
Phone: 416-586-4553
MD, PhD, FRCP(C)
Associate Professor
Primary Research Area: Infectious Diseases & Immunopathology

My research is focused on the epidemiology and prevention of hospital-acquired infections, antibiotic resistant pathogens and C.difficile.  I am also interested in antimicrobial stewardship and the use of cumulative antibiogram data to guide empiric treatment.

Phone: 416-864-5568
MB, BCH, MRCPath
Associate Professor
Research Location: Toronto General Hospital/Research Institute (UHN)
Primary Research Area: Cancer
Phone: 416-340-3072
MD, MSc, FRCPC
Professor
Research Location: St. Michael's Hospital/Research Institute
Primary Research Area: Brain & Neuroscience
Secondary Research Area: Cancer

His  research interest is focused on neuropathology, particularly the mechanisms of development and progression of degenerative diseases of the brain, including Alzheimer's disease, the non-Alzheimer dementias, movement disorders, and amyotrophic lateral sclerosis.He also publishes regularly on neuro-oncology and diagnostic aspects of general neuropathology.

Phone: 416-864-6060
Ext: 3418
MD, FCAP, FASCP, FRCPC
Lecturer
Research Location: Toronto General Hospital/Research Institute (UHN)

Mixed phenotype acute leukemias

Phone: 416-340-4800
Ext: 2381

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