LMP340H1 - Introduction to Pathobiology I

Course description

Concepts in:

  • pathogenesis
  • cell injury
  • adaptation and death
  • oxidative stress
  • ion channels and pumps
  • calcium homeostasis.

Molecular basis of diseases affecting iron, blood and the cardiovascular system.

The laboratory examines anatomical and histopathological specimens in cardiac disease.

Course coordinator

Dr. Doug Templeton

Office address: 1 King’s College Circle, MSB 6275

doug.templeton@utoronto.ca

Teaching assistant

Kristiana Xhima

kristiana.xhima@mail.utoronto.ca

 

Term

Fall 2020

Class location and time:

Wednesday 9:00-11:00 am

PB255 (Leslie L. Dan Pharmacy Building, 144 College St.)

Tutorial location and time

Wednesday 11:00-12:00pm

PB255 (Leslie L. Dan Pharmacy Building, 144 College St.)

Office hours

Contact TA or instructors

Course details

  • Hours: 24L/12T
  • Prerequisite information: Enrolment is limited to students specialized in Pathobiology who have completed, or are completing, the first and second year requirements of the program.
  • Prerequisites: n/a
  • Exclusions: LMP300Y1, LMP301H1, LMP363H1
  • Distribution requirements: Science
  • Breadth requirement: Living Things and Their Environment (4)
  • Enrolment limits: 40 students

Student evaluation

Term test (1 h, multiple choice) – 20 %

Lab test – 10 %

Assignment (1500-word essay, due last Monday of classes) – 30 %

Final exam (2 h, short answer and essay, cumulative) – 40 %

See information on Academic Integrity

Schedule

Date

Title

Instructor

Dates TBC

Course Introduction and cell injury

Doug Templeton

 

Cell death and adaptation

Doug Templeton

 

Oxygen and oxidative stress

Doug Templeton

 

Ion channels and pumps

Doug Templeton

 

Calcium

Doug Templeton

 

Hematopoiesis and hemolytic disease

Doug Templeton

 

Iron metabolism and thalassemia

Doug Templeton

 

Term test (11:00-12:00)

 

 

Cardiovascular Lab

Jagdish Butany

 

Cardiovascular Lab

Jagdish Butany

 

Cardiovascular pathobiology I

Avrum Gotlieb

 

Cardiovascular pathobiology II

Avrum Gotlieb

 

Cardiovascular Lab/Test

Jagdish Butany

 

Final Exam

 

Recommended reading or text book

None