LMP340H1 - Introduction to Pathobiology I

Course description

Concepts in:

  • pathogenesis
  • cell injury
  • adaptation and death
  • oxidative stress
  • ion channels and pumps
  • calcium homeostasis.

Molecular basis of diseases affecting iron, blood and the cardiovascular system.

The laboratory examines anatomical and histopathological specimens in cardiac disease.

Course coordinator

Dr Doug Templeton

Office address: 1 King’s College Circle, MSB 6275


Teaching assistant

Kristiana Xhima



Term Fall 2020
Class location and time:

Wednesday 9:00-11:00 am

PB255 (Leslie L. Dan Pharmacy Building, 144 College St.)

Tutorial location and time

Wednesday 11:00-12:00pm

PB255 (Leslie L. Dan Pharmacy Building, 144 College St.)

Office hours Contact TA or instructors

Course details

  • Hours: 24L/12T
  • Prerequisite information: Enrolment is limited to students specialized in Pathobiology who have completed, or are completing, the first and second year requirements of the program.
  • Prerequisites: n/a
  • Exclusions: LMP300Y1, LMP301H1, LMP363H1
  • Distribution requirements: Science
  • Breadth requirement: Living Things and Their Environment (4)
  • Enrolment limits: 40 students

Student evaluation

Term test (1 h, multiple choice) – 20 %

Lab test – 10 %

Assignment (1500-word essay, due last Monday of classes) – 30 %

Final exam (2 h, short answer and essay, cumulative) – 40 %

See information on Academic Integrity



Date Title Instructor
Dates TBC Course Introduction and cell injury Doug Templeton
  Cell death and adaptation Doug Templeton
  Oxygen and oxidative stress Doug Templeton
  Ion channels and pumps Doug Templeton
  Calcium Doug Templeton
  Hematopoiesis and hemolytic disease Doug Templeton
  Iron metabolism and thalassemia Doug Templeton
  Term test (11:00-12:00)  
  Cardiovascular Lab Jagdish Butany
  Cardiovascular Lab Jagdish Butany
  Cardiovascular pathobiology I Avrum Gotlieb
  Cardiovascular pathobiology II Avrum Gotlieb
  Cardiovascular Lab/Test Jagdish Butany
  Final Exam  

Recommended reading or text book