LMP340H1 - Introduction to Pathobiology I

Course description

Concepts in:

  • pathogenesis
  • cell injury
  • adaptation and death
  • oxidative stress
  • ion channels and pumps
  • calcium homeostasis.

Molecular basis of diseases affecting iron, blood and the cardiovascular system.

The laboratory examines anatomical and histopathological specimens in cardiac disease.

Course coordinator

Dr. Doug Templeton

Office address: 1 King’s College Circle, MSB 6275


Teaching assistant

Kristiana Xhima




Fall 2020

Class location and time:

Wednesday 9:00-11:00 am

PB255 (Leslie L. Dan Pharmacy Building, 144 College St.)

Tutorial location and time

Wednesday 11:00-12:00pm

PB255 (Leslie L. Dan Pharmacy Building, 144 College St.)

Office hours

Contact TA or instructors

Course details

  • Hours: 24L/12T
  • Prerequisite information: Enrolment is limited to students specialized in Pathobiology who have completed, or are completing, the first and second year requirements of the program.
  • Prerequisites: n/a
  • Exclusions: LMP300Y1, LMP301H1, LMP363H1
  • Distribution requirements: Science
  • Breadth requirement: Living Things and Their Environment (4)
  • Enrolment limits: 40 students

Student evaluation

Term test (1 h, multiple choice) – 20 %

Lab test – 10 %

Assignment (1500-word essay, due last Monday of classes) – 30 %

Final exam (2 h, short answer and essay, cumulative) – 40 %

See information on Academic Integrity





Dates TBC

Course Introduction and cell injury

Doug Templeton


Cell death and adaptation

Doug Templeton


Oxygen and oxidative stress

Doug Templeton


Ion channels and pumps

Doug Templeton



Doug Templeton


Hematopoiesis and hemolytic disease

Doug Templeton


Iron metabolism and thalassemia

Doug Templeton


Term test (11:00-12:00)



Cardiovascular Lab

Jagdish Butany


Cardiovascular Lab

Jagdish Butany


Cardiovascular pathobiology I

Avrum Gotlieb


Cardiovascular pathobiology II

Avrum Gotlieb


Cardiovascular Lab/Test

Jagdish Butany


Final Exam


Recommended reading or text book