LMP365H1 - Neoplasia 20L 4P

Course description

A general introduction to the cellular and molecular aspects of cancer and its etiology.

The laboratory component presents the range of benign and malignant tumor types at the gross and histological levels.

Pathophysiology of cancer – tumorigenesis, invasion/ metastases, analytical and therapeutic strategies.

Course coordinator

Dr. Harry Elsholtz

Office address: 1 King’s College Circle, MSB 6207


Teaching assistant

Evan Lubanszky



 Winter 2022

Class location and time

Thursday 1 - 3 pm


Tutorial location and time

To be announced

Office hours

Meeting times can be arranged with course coordinator

Course details

  • Hours: 20L/4P
  • Corequisite: LMP340H1 or permission of department
  • Exclusions: none
  • Distribution requirements: Science
  • Breadth requirement: Living Things and Their Environment (4)
  • Enrolment limits: 35 students

Student evaluation

Online Pathology Lab Test: 20%

Online Midterm Test: 35%

Online Final Exam: 45%

See information on Academic Integrity





January 13, 2022

Introduction and overview


DNA Damage/ Repair

Dr. Harry Elsholtz

January 20, 2022

MMR and Hypermutation in Human Cancer

Dr. Adam Shlien

January 27, 2022

BRCA in Cancer

Dr. Razqallah Hakem

February 3, 2022

Pathology Laboratory I

Dr. Irene Xie

Dr. Susan Armstrong

February 10, 2022

Pathology Laboratory II

Lab Test (20%)

Dr. Irene Xie

Dr. Susan Armstrong

February 17, 2022

Cancer Hallmarks; Hypoxia and Cancer Biology    

Dr. Michael Ohh

February 24, 2022

Reading Week


March 3, 2022

Midterm Test (35%)

Dr. Harry Elsholtz

March 10, 2022

Cancer Invasion and Metastasis

Dr. Marco Magalhaes

17 March, 2022

Computational Biology in Cancer

Dr. Bo Wang

MArch 24, 2022

Cancer Metabolism and Metastasis

Dr. Eldad Zacksenhaus

March 31, 2022

Cancer Biomarkers and Personalized Medicine

Dr. Shamini Selvarajah

April 7, 2022

Next Generation Sequencing: new applications in the cancer field

Cancer Modelling  (45 minute seminar)

Sachin Kumar

Evan Lubanszky


Final Exam (45%)

Dr. Harry Elsholtz

Evan Lubanszky