A 12-year-old patient presents to their family physician with a large abdominal mass as well as decrease in appetite and weight loss. The patient has no history of fever or hematuria. CT imaging demonstrated near complete replacement of the right kidney by tumour (19.8cm) with direct extension into the right adrenal gland and liver. Two separate 12 cm masses were also identified within the liver. Laboratory studies demonstrated normal HVA/VMA, AFP, HCG, INR, PTT
Questions:
Based on the clinical information provided, what is your differential diagnosis for a kidney mass in a 12-year-old child?
What tumours are associated with the following biochemical markers:
HVA/VMA
AFP
HCG
Review the two H&E images below. What is your new differential diagnosis?
How to participate
Take a look at the H&E images.
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