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Mar 21, 2022  |  4:00pm - 5:00pm

Smooth muscle cell pathobiology in cardiovascular disease

Type
LMP seminar series
Tag(s)
Impactful research

As part of our Monday seminar series, we are delighted to welcome our speaker:

Dr. Daniel Greif, MD
Associate Professor with Tenure
Departments of Medicine (Cardiovascular) and Genetics
Co-director, Yale Cardiovascular Research Center, Yale University School of Medicine

Hosted by

Michelle Bendeck

How to join

An email including Zoom link will be sent to the LMP community.

If you are not part of LMP and wish to join this talk, please contact:

Louella D'Cunha

lmp.undergrad@utoronto.ca

Speaker: Daniel Greif

Dan is Associate Professor with Tenure in Departments of Medicine (Cardiovascular) and Genetics and a cardiologist at Yale University. Dan is co-Director of the Yale Cardiovascular Research Center.

He received a B.S. in chemical engineering from Stanford University and M.D. from UCSF. Dan took a year off from medical school and conducted research in Dr. F. William Luscinskas’ lab at Harvard, studying leukocyte-endothelial cell adhesion. He then was a medical resident at University of Washington and at Brigham & Women’s Hospital. After residency, he continued at Brigham & Women’s Hospital as a postdoctoral fellow in Dr. Thomas Michel’s lab, studying biochemistry of eNOS and calmodulin. Dan then returned to Stanford for cardiology fellowship and further postdoctoral training, investigating pulmonary artery morphogenesis in Dr. Mark Krasnow’s lab.   

Dan’s lab at Yale utilizes multi-disciplinary approaches to study how blood vessels form, are maintained and go awry in disease. They primarily focus on vascular mural cells (i.e., smooth muscle cells and pericytes). In addition, Dan’s lab studies the role of alveolar myofibroblasts in lung development and fibrosis. Furthermore, they investigate how these cell types interface with other cell types, including endothelial and inflammatory cells.

Dan’s lab aims to gain critical insights into pathogenesis of diverse cardiovascular and pulmonary pathologies and leverage these insights into novel therapeutics to ameliorate human disease.

Dan is committed to engaging young trainees of diverse backgrounds in vascular research and bridging the gap between studies of vascular development and disease to translate fundamental discoveries to human disease. For more information, please visit Dan’s lab website email Dan at: daniel.greif@yale.edu
 

Daniel Greif