LMP1203H: Basic principles of analytical clinical biochemistry
Who can attend
The course is open to medical biochemistry residents, postdoctoral diploma in clinical chemistry fellows, and graduate students.
Graduate students need permission from the supervisor and must be registered in the LMP graduate program to attend.
No specific course is required.
This course introduces current analytical techniques as applied in clinical biochemistry laboratories. We will cover the theoretical aspects of each technique, the limitations, and common applications. The course also introduces analytical and clinical evaluation of laboratory methods.
The course will be run as tutorials/lectures for medical biochemistry residents, postdoctoral diploma in clinical chemistry fellows, and graduate students.
Meetings will take place on Wednesday mornings (9:00-12:00 noon). Alternative meeting times and places may be arranged with individual lecturers if deemed necessary.
Davor Brinc, PhD, FCACB
email@example.com for administrative queries.
Timings and location
This course is offered every year in the Fall session.
Wednesdays, (9:00 a.m. - 12:00 noon)
Location: MS 3290 (note that selected lectures will be delivered via Zoom; we will email details for those in advance)
The students are responsible for the material provided in the lectures.
Selected chapters from Nader Rifai (editor). Tietz Textbook of Clinical Chemistry and Molecular Diagnostics.
Supplementary readings can also be provided by each lecturer
Final end-of-course exam.
Take-home assignments to be submitted on the day of the final exam may be used if deemed appropriate by the individual faculty member.
Lectures will be in person unless stated via Zoom.
|September 8, 2021||Analytical method evaluation||Dr. Davor Brinc (UHN)|
|September 15, 2021||
Clinical method evaluation
Dr. Dorothy Truong, LifeLabs
|September 22, 2021||
General lab techniques: centrifugation, water purification, osmometry, radioactivity, viscometry, dialysis, freeze drying, buffers
|Dr. Felix Leung|
|September 29, 2021||
Enzymatic techniques and chemistry analyzers
|Dr. Felix Leung|
|October 6, 2021||
Spectrophotometry: reflectance, absorbance, transmittance, turbidimetry, nephelometry, flameemission/absorption, IR, NMR, fluorescence
Dr. Sarah Delaney, Unity Health Toronto (Sarah.Delaney@
|October 13, 2021||
|Dr. Saranya Arnoldo|
|October 20, 2021||
Electrochemistry applications in a clinical chemistry laboratory
|Dr. Mohamed Abouelhassan|
October 27, 2021
Immunoassays I: properties of antibodies and antigens; Ag-Ab interactions; Ab production
|Dr. Paul Yip|
|November 3, 2021||Immunoassays II: configurations, labels, and interferences||Dr. Paul Yip|
|November 10, 2021||
|Dr. Daniel Beriault|
|November 17, 2021||
|Dr. Andrea Bozovic|
|November 24, 2021||
|Dr. Davor Brinc|
|December 1, 2021||
|Dr. Cuihong Wei|
|December 8, 2021||
Ultracentrifugation and lipid analyses
Dr. Dana Bailey, Dynacare (BaileyD@dynacare.ca)
|December 15, 2021||Final Examination||Dr. Davor Brinc|