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LMP1203H: Basic principles of analytical clinical biochemistry

Who can attend

The course is open to medical biochemistry residents, postdoctoral diploma in clinical chemistry fellows, and graduate students.

Graduate students need permission from the supervisor and must be registered in the LMP graduate program to attend.

Prerequisites

Undergraduate course in biochemistry and/or molecular biology is recommended.

Course description

This course introduces current analytical techniques as applied in clinical biochemistry laboratories. We will cover the theoretical aspects of each technique, the limitations, and common applications. The course also introduces analytical and clinical evaluation of laboratory methods.

The course will be run as tutorials/lectures for medical biochemistry residents, postdoctoral diploma in clinical chemistry fellows, and graduate students.

Course coordinator

Dr. Davor Brinc

davor.brinc@uhn.ca

lmp.grad@utoronto.ca for administrative queries.

Timings and location

Drop date: October 26, 2026

This course is offered every year in the Fall session.

  • Wednesdays, 9 am - 12 noon
  • Location: Health Sciences Building (155 College Street) Room 705

Meetings will take place on Wednesday mornings (9:00-12:00 noon). Alternative meeting times and places may be arranged with individual lecturers if deemed necessary.

Readings

Students are responsible for the material provided in the lectures.

Optional readings

Selected chapters from N. Rifai et al (editors). Tietz Textbook of Laboratory Medicine.

Supplementary readings can also be provided by each lecturer.

Evaluation methods

  • Mid-term (sessions 1 to 5): 25%
  • Final exam (sessions 6 to 14): 45% 
  • Take-home assignment: 30%

Schedule

Session #

Date

Topic

Lecturer/instructor

1

September 9, 2026

Introduction to analytical clinical biochemistry and analytical method evaluation 

Dr. Jessica Miller, UHN

jessica.miller@uhn.ca

2

September 16, 2026

Clinical method evaluation

Dr. Dorothy Truong, LifeLabs

dorothy.truong@lifelabs.com

3

September 23, 2026

General lab techniques

Dr. Ashley DiMeo, UHN

ashley.dimeo2@uhn.ca

4

September 30, 2026

Enzymatic techniques and chemistry analyzers

Dr. Sean Campbell, Mount Sinai Hospital

Sean.Campbell@sinaihealth.ca

5

October 7, 2026

Electrochemistry applications in clinical chemistry laboratory 

Dr. Mohamed Abouelhassan, Sunnybrook Health Sciences Centre

mohamed.abouelhassan@sunnybrook.ca

6

October 14, 2026

Mass Spectrometry 

Dr. Jessica Miller, UHN

jessica.miller@uhn.ca

Mid Term

October 16, 2026

Midterm

Location: MSB6222 – Large Meeting Room

Dr. Davor Brinc, UHN

davor.brinc@uhn.ca

7

October 21, 2026

Immunoassays I

Dr. Paul Yip, Sunnybrook Health Sciences Centre

paul.yip@sunnybrook.ca

8

October 28, 2026

Spectrophotometry

Dr. Matthew Lafreniere, Sunnybrook Health Sciences Centre

matthew.lafreniere@sunnybrook.ca

9

November 4, 2026

Immunoassays II

Dr. Paul Yip, Sunnybrook Health Sciences Centre

paul.yip@sunnybrook.ca

10

November 11, 2026

Chromatography

Dr. Daniel Beriault, Unity Health Toronto

daniel.beriault@unityhealth.to

11

November 18, 2026

Electrophoresis

Dr. Saranya Arnoldo, Unity Health Toronto

Saranya.Arnoldo@unityhealth.to

12

November 25, 2026

Point-of-care testing

Dr. Davor Brinc, UHN

davor.brinc@uhn.ca

13

December 2, 2026

Molecular diagnostics

Dr. Cuihong Wei, UHN

cuihong.wei@uhn.on.ca

14

December 9, 2026

Ultracentrifugation and lipid analyses

Dr. Dana Bailey, LifeLabs

dana.nyholt@lifelabs.com

Final Exam

December 16, 2026

Final exam

Dr. Davor Brinc, UHN

davor.brinc@uhn.ca