LMP1203H: Basic principles of analytical clinical biochemistry
Who can attend
The course is open to medical biochemistry residents, postdoctoral diploma in clinical chemistry fellows, and graduate students.
Graduate students need permission from the supervisor and must be registered in the LMP graduate program to attend.
Prerequisites
Undergraduate course in biochemistry and/or molecular biology is recommended.
Course description
This course introduces current analytical techniques as applied in clinical biochemistry laboratories. We will cover the theoretical aspects of each technique, the limitations, and common applications. The course also introduces analytical and clinical evaluation of laboratory methods.
The course will be run as tutorials/lectures for medical biochemistry residents, postdoctoral diploma in clinical chemistry fellows, and graduate students.
Course coordinator
lmp.grad@utoronto.ca for administrative queries.
Timings and location
This course is offered every year in the Fall session.
Wednesdays, 9 am - 12 noon
Location: SS 2112 (Sidney Smith Hall)
Meetings will take place on Wednesday mornings (9:00-12:00 noon). Alternative meeting times and places may be arranged with individual lecturers if deemed necessary.
Readings
Students are responsible for the material provided in the lectures.
Optional readings
Selected chapters from N. Rifai et al (editors). Tietz Textbook of Laboratory Medicine.
Supplementary readings can also be provided by each lecturer.
Evaluation methods
- Take-home assignment: 10%
- Mid-term (sessions 1 to 6): 40%
- Final exam (session 7, 9-15): 50%
Schedule
Lectures will be in person unless stated via Zoom. Zoom details will be provided by email.
Date |
Topic |
Lecturer/instructor |
---|---|---|
September 4, 2024 |
Introduction to analytical clinical biochemistry and analytical method evaluation |
Dr. Jessica Miller, UHN (jessica.miller@uhn.ca ) |
September 11, 2024 |
Clinical method evaluation Online via Zoom |
Dr. Dorothy Truong, LifeLabs (dorothy.truong@lifelabs.com) |
September 18, 2024 |
General lab techniques |
Dr. Ashley DiMeo, UHN (ashley.dimeo2@uhn.ca) |
September 25, 2024 |
Electrochemistry applications in clinical chemistry laboratory Online via Zoom |
Dr. Mohamed Abouelhassan, LifeLabs (mohamed.abouelhassan@lifelabs.com) |
October 2, 2024 |
Enzymatic techniques and chemistry analyzers |
Dr. Felix Leung, Mount Sinai Hospital (felix.leung@sinaihealth.ca) |
October 9, 2024 |
Electrophoresis |
Dr. Saranya Arnoldo, Trillium (saranya.arnoldo@thp.ca) |
October 16, 2024 |
Spectrophotometry Online via Zoom |
Dr. Uvaraj Uddayasankar, LifeLabs (uvaraj.uddayasankar@lifelabs.com) |
October 23, 2024 |
Midterm |
Dr. Davor Brinc, UHN (davor.brinc@uhn.ca) |
October 30, 2024 |
Immunoassays I |
Dr. Paul Yip, Sunnybrook Health Sciences Centre (paul.yip@sunnybrook.ca) |
November 6, 2024 |
Immunoassays II |
Dr. Paul Yip, Sunnybrook Health Sciences Centre |
November 13, 2024 |
Chromatography |
Dr. Daniel Beriault, Unity Health Toronto (daniel.beriault@unityhealth.to) |
November 20, 2024 |
Mass Spectrometry |
Dr. Andrea Bozovic, UHN (andrea.bozovic@uhn.ca) |
November 27, 2024 |
Point-of-care testing |
Dr. Davor Brinc, UHN |
December 4, 2024 |
Molecular diagnostics |
Dr. Cuihong Wei, UHN (cuihong.wei@uhn.on.ca) |
December 11, 2024 |
Ultracentrifugation and lipid analyses |
Dr. Dana Bailey, Dynacare (BaileyD@dynacare.ca) |
December 18, 2024 |
Final exam |
Dr. Davor Brinc, UHN |