LMP1203H: Basic principles of analytical clinical biochemistry
Who can attend
The course is open to medical biochemistry residents, postdoctoral diploma in clinical chemistry fellows, and graduate students.
Graduate students need permission from the supervisor and must be registered in the LMP graduate program to attend.
Prerequisites
Undergraduate course in biochemistry and/or molecular biology is recommended.
Course description
This course introduces current analytical techniques as applied in clinical biochemistry laboratories. We will cover the theoretical aspects of each technique, the limitations, and common applications. The course also introduces analytical and clinical evaluation of laboratory methods.
The course will be run as tutorials/lectures for medical biochemistry residents, postdoctoral diploma in clinical chemistry fellows, and graduate students.
Course coordinator
lmp.grad@utoronto.ca for administrative queries.
Timings and location
This course is offered every year in the Fall session.
Wednesdays, 9 am - 12 noon
Location: MSB 3290
Meetings will take place on Wednesday mornings (9:00-12:00 noon). Alternative meeting times and places may be arranged with individual lecturers if deemed necessary.
Readings
Students are responsible for the material provided in the lectures.
Optional readings
Selected chapters from N. Rifai et al (editors). Tietz Textbook of Laboratory Medicine.
Supplementary readings can also be provided by each lecturer.
Evaluation methods
Final end-of-course exam (lectures 3,4,6,8,9,10,13,14): 57%
Take-home assignments for selected lectures (indicated in the table below): 43%
Schedule
Lectures will be in person unless stated via Zoom. Zoom details will be provided by email.
Date |
Topic |
Lecturer/instructor |
---|---|---|
September 13, 2023 |
Introduction to analytical clinical biochemistry Analytical method evaluation Take-home assignment |
Dr. Davor Brinc, UHN |
September 20, 2023 |
Clinical method evaluation Via Zoom Take-home assignment |
Dr. Dorothy Truong, LifeLabs (dorothy.truong@lifelabs.com) |
September 27, 2023 |
General lab techniques |
Dr. Ashley DiMeo, UHN |
October 4, 2023 |
Enzymatic techniques and chemistry analyzers |
Dr. Felix Leung, Mount Sinai Hospital |
October 11, 2023 |
Spectrophotometry Take-home assignment |
Dr. Uvaraj Uddayasankar, LifeLabs (uvaraj.uddayasankar@ |
October 18, 2023 |
Electrophoresis Via Zoom |
Dr. Saranya Arnoldo, Trillium |
October 25, 2023 |
Electrochemistry applications in a clinical chemistry laboratory Take-home assignment Via Zoom |
Dr. Mohamed Abouelhassan, LifeLabs |
November 1, 2023 |
Immunoassays I |
Dr. Paul Yip, Sunnybrook Health Sciences Centre |
November 8, 2023 |
Immunoassays II |
Dr. Paul Yip, Sunnybrook Health Sciences Centre |
November 15, 2023 |
Chromatography |
Dr. Daniel Beriault, Unity Health Toronto |
November 22, 2023 |
Mass Spectrometry Take-home assignment |
Dr. Andrea Bozovic, UHN |
November 29, 2023 |
Point-of-care testing Take-home assignment |
Dr. Davor Brinc, UHN |
December 6, 2023 |
Molecular diagnostics Via Zoom |
Dr. Cuihong Wei, UHN |
December 13, 2023 |
Ultracentrifugation and lipid analyses Via Zoom |
Dr. Dana Bailey, Dynacare (BaileyD@dynacare.ca) |
December 20, 2023 |
Final exam |
Dr. Davor Brinc, UHN |