LMP1203H: Basic principles of analytical clinical biochemistry
Who can attend
To attend this course, you must have permission from your supervisor and be:
- registered in our graduate program; or
- be a medical or clinical biochemistry resident or fellow.
Course description
You will learn about modern analytical techniques and limitations as applied in clinical laboratories.
Topics include the basic theory and applications of analytical techniques that are commonly used in clinical laboratories.
Course coordinator
Dr. Pak-Cheung Chan
pc.chan@sunnybrook.ca
lmp.grad@utoronto.ca for administrative queries.
Timings and location
This course is offered every year in the Fall session.
Wednesdays, (9:00 a.m. - 12:00 noon)
Location: Synchronous online delivery (Zoom)
Evaluation methods
Home assignments and final end-of-course exam.
Schedule
| Date | Topic | Lecturer/instructor |
|---|---|---|
| September 2, 2020 | Method evaluation, analytical & clinical | Dr. Davor Brinc |
| September 9, 2020 |
General lab techniques: centrifugation, water purification and QA osmometry, radioactivity, viscometry, dialysis, freeze drying, buffers, etc |
Dr. Felix Leung |
| September 16, 2020 |
Enzymatic techniques and chemistry analyzers |
Dr. Felix Leung |
| September 23, 2020 |
Co-oximetry, Biosensors, Nanotechnology and POC instruments |
Dr. Davor Brinc |
| September 30, 2020 |
Ion selective electrodes |
Dr. Mohamed Abouelhassan |
| October 7, 2020 | Electrophoresis and related techniques | Dr. Pak-Cheung Chan |
| October 14, 2020 | Chromatographic techniques: TLC, LC, GC, HPLC | Dr. Daniel Beriault |
|
October 23, 2020 Friday |
Mass Spectrometry Friday, not Wednesday. |
Dr. Vathany Kulasingam |
| October 28, 2020 | Immunoassays I: Properties of Antibodies and Antigens; Ag-Ab Interactions; Ab production | Dr. Paul Yip |
| November 4, 2020 |
Immunoassays II: Configurations, Labels and Interferences |
Dr. Paul Yip |
| November 11, 2020 |
Immunoassays III: Fluorescence and Luminescence |
Dr. Pak-Cheung Chan |
| November 18, 2020 |
Spectrophotometric techniques: reflectance, absorbance, transmittance, turbidimetry and nephelometry; Flame emission and absorption spectrometry; Infra-red, and NMR. |
Dr. Maria Pasic |
| November 25, 2020 |
Misc Techniques 1: Molecular diagnostics |
Dr. Cuihong Wei |
| December 2, 2020 |
Misc Techniques 2: Ultracentrifugation and lipid analyses |
Dr. Dana Bailey Dynacare |
| December 9, 2020 | Final Examination (3 hours) | Dr. Pak-Cheung Chan |