LMP440H1 – Mechanisms of Host-Microbe Interactions

Course description

Mechanisms that allow microbial pathogens to cause disease and the host to detect infection, mount an inflammatory response and resolve the infection. Primary research articles are discussed. Topics include commensal and pathogenic bacteria, microbe recognition, programmed cell death, immunometabolism, inflammatory diseases.

Mechanisms that allow microbial pathogens to cause disease and the host to detect infection, mount an inflammatory response and resolve the infection. Primary research articles are discussed. Topics include commensal and pathogenic bacteria, microbe recognition, programmed cell death, immunometabolism, inflammatory diseases.

Topics include:

• commensal and pathogenic bacteria
• microbe recognition
• programmed cell death
• immunometabolism
• inflammatory diseases.

Course coordinators

Dr. Jeremy Mogridge

Office address: 1 King’s College Circle, MSB Room 6306
jeremy.mogridge@utoronto.ca

Teaching assistant

Adrienne Ranger

adrienne.ranger@mail.utoronto.ca

Course details

• Hours: 24L
• Prerequisite: (IMM340H1, IMM350H1)/ (IMM341H1, IMM351H1) / 
  (MGY377H1, MGY378H1) / LMP310H1. Pre-requisite waiver requests must be made to the academic unit (lmp.undergraduate@utoronto.ca).
• Exclusions: LMP402H1, LMP436H1 
• Recommended preparation: None
• Distribution requirements: Science
• Breadth requirement: Living Things and Their Environment (4)          
• Enrolment limits: 30 students

Student evaluation

Midterm: 45% - due date 21 October, 2026

Assignment: 10% - due date 10 October, 2026

Final Exam: 45%

See information on Academic Integrity

Schedule for Fall 2026

Lecture topics are subject to change. We will list finalized lecture topics in the official syllabus