LMP460H1 – Pathobiology of the Cardiovascular System
Course description
This course covers the pathobiology of the heart, blood vessels, and lymphatic system.
The emphasis is on the underlying cell biology of processes such as:
- Vascular Malformations: congenital and acquired
- Atherosclerosis: Pathogenesis, Inflammation, Advanced Complications, Animal Models
- Treatments of vascular disease
- Regenerative Medicine in the Cardiovascular System
Course coordinators
Office address: 661 University Ave, MaRS II, 14th floor, Rm 1432
michelle.bendeck@utoronto.ca
Teaching assistant
Amanda Mao
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Term |
Winter 2023 |
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Class location and time |
Tuesday 10 am - 12 pm UC 52 University College, 15 King’s College Circle |
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Office hours |
Contact TA or Course Coordinators |
Course details
- Hours: 24L
- Prerequisite: (PSL300H1, PSL301H1) / PSL302Y1
- Exclusions: None
- Recommended preparation: None
- Distribution requirements: Science
- Breadth requirement: Living Things and Their Environment (4)
- Enrolment limits: 30 students
Student evaluation
Midterm test: 40%
Final exam: 60%
See information on Academic Integrity
Schedule
Lecture topics are subject to change. We will list finalized lecture topics in the official syllabus.
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Date |
Topic |
Instructor |
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Lecture 1 |
Vascular and Cardiac Structure and Function |
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Lecture 2 |
Introduction to atherosclerosis |
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Lecture 3 |
Animal models of atherosclerosis |
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Lecture 4 |
Inflammatory Mechanisms of Atherosclerosis |
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Lecture 5 |
microRNA regulation in atherosclerosis |
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Lecture 6 |
Cardiovascular regeneration |
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Lecture 7 |
Vascular Calcification |
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Lecture 8 |
Vascular Development |
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Lecture 9 |
Vascular Malformations |
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Lecture 10 |
New Technologies to Monitor CV disease |
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Lecture 11 |
Tissue Engineering Approaches for cardiovascular disease |
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Recommended reading or text book
None.