LMP460H1 – Pathobiology of the Cardiovascular System
Course description
This course covers the pathobiology of the heart, blood vessels, and lymphatic system.
The emphasis is on the underlying cell biology of processes such as:
- congenital diseases of the heart
- ischemic injury
- stroke
- treatments of vascular disease
- cardiovascular biomaterials
- atherosclerosis
- hypertension.
Course coordinators
Office address: 661 University Ave, MaRS II, 14th floor, Rm 1432
michelle.bendeck@utoronto.ca
Teaching assistant
Quinn Bonafiglia
quinn.bonafiglia@mail.utoronto.ca
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Term |
Winter 2023 |
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Class location and time |
Tuesday 10 am - 12 pm Location TBC |
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Office hours |
Contact TA or Course Coordinators |
Course details
- Hours: 24L
- Prerequisite: (PSL300H1, PSL301H1) / PSL302Y1
- Exclusions: None
- Recommended preparation: None
- Distribution requirements: Science
- Breadth requirement: Living Things and Their Environment (4)
- Enrolment limits: 30 students
Student evaluation
Midterm test: 40%
Article assignment: 20%
Final exam: 40%
See information on Academic Integrity
Schedule
Lecture topics are subject to change. We will list finalized lecture topics in the official syllabus
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Date |
Topic |
Instructor |
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Lecture 1 |
Introduction to cardiovascular pathobiology |
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Lecture 2 |
Vascular development and angiogenesis |
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Lecture 3 |
Atherogenesis |
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Lecture 4 |
Platelet function and thrombosis |
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Lecture 5 |
Animal models |
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Lecture 6 |
Inflammatory mechanisms |
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Lecture 7 |
Lipids |
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Lecture 8 |
Hypertension |
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Lecture 9 |
Clinical perspectives and treatments for athersclerosis |
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Lecture 10 |
Vascular malformations |
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Lecture 11 |
Diabetes and the microvasculature |
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Recommended reading or text book
None.