LMP1207H: Mass spectrometry, proteomics and their clinical applications
Who can attend
You must be registered in a graduate program to attend this course.
This course is open to all graduate students at the University of Toronto, provided you have pre-approval from your department and the course coordinators.
Course description
You will learn the fundamentals of mass spectrometry and its use with biochemical techniques to provide analyses of proteins and small molecules.
You will also study the interface with bioinformatics and other -omics technologies.
The second half of the course is designed to bridge the gap between basic and translational sciences and will examine the research and clinical applications of mass spectrometry.
Course coordinators
lmp.grad@utoronto.ca for administrative queries.
Timings and location
This course is offered every even year in the Fall term (i.e. 2020, 2022 etc).
Wednesdays 10 am – 12 pm
Location: HS 705, Health Sciences Building 155 College Street, Toronto
Evaluation methods
Two written examinations:
- Mid-term - 30%
- Final exam - 30%
Presentation of a journal article - 20%
Take-home assignment - 20%
Schedule
|
Date |
Topic |
Lecturer/instructor |
|---|---|---|
|
September 7, 2022 |
Introduction to mass spectrometry and proteomics |
|
|
September 14, 2022 |
Basic principles of mass spectrometry |
|
|
September 21, 2022 |
Fundamentals of proteomics |
|
|
September 28, 2022 |
Bioinformatics: Protein Identification and Targeted Proteomics |
|
|
October 5, 2022 |
Integration of proteomics with other -omics technologies |
Dr. Voisin |
|
October 12, 2022 |
Post-translational modifications and Protein-protein interactions |
Dr. Kuzmanov |
|
October 19, 2022 |
Mid-Term Exam |
|
|
October 26, 2022 |
Analytical workflows for sub-proteome analyses |
|
|
November 2, 2022 |
Mass spectrometry for metabolic and molecular genetics |
|
|
November 9, 2022 |
Mass Spectrometry Imaging |
Dr. Zarrine-Afsar |
|
November 16, 2022 |
Clinical microbiology and toxicology |
Dr. Stefan |
|
November 23, 2022 |
Global Metabolomics |
Dr. Nikita Looby |
|
November 30, 2022 |
Emerging applications of Proteomics and MS |
|
|
December 7, 2022 |
Final Exam |