Cancer is the leading cause of premature death in Canada.
Each year, there will be more than 175,000 new cases and approximately 75,000 deaths from this disease. This means that every day, an estimated 500 Canadians will be diagnosed with cancer and another 200 will die.
To improve cancer treatment and reduce the burden of this disease, our researchers strive to expand their understanding of cancer biology.
By using multi-disciplinary approaches, they elucidate the underpinnings of cancer hallmarks and translate these discoveries into novel cancer therapeutics.
Our researchers focus on various aspects related to key hallmarks of cancer such as:
- genome instability and alterations
- cell death resistance
- proliferative signalling
- evasion of growth suppressors
- replicative immortality
- energy metabolism
- cancer stem cells
- inflammation and immune evasion