LMP1100H: Cellular imaging in pathobiology
Who can attend
No specific courses are required, however, you should have successfully completed advanced courses in molecular biology, cell biology and/or biochemistry.
Priority will be given to postgraduate, senior PhD, and MD students.
Course description
This course explores the powerful intersection of physics, biological sciences, artificial intelligence (AI), and imaging technologies.
This course will focus on the theory, application, and implementation of different imaging techniques and, more importantly, on the application of biological experimentation relevant to modern biological research, clinical, biochemical studies, and common real-life research goals in industry, hospitals, and research laboratories.
Additionally, we will outline strategies for effective communication and explore how enhancing your communication skills can propel your career and improve your science communication with experts, investors, funding agencies, and the public.
We will also cover intellectual property (IP) rights, strategies, and methods for safeguarding your creations and inventions.
Methodologies:
- 3D scanning electron microscopy
- compound, scanning and transmission electron microscopes
- the latest image analysis software, AI, machine learning software for image analysis
- digital pathology
- optophysiology
- light microscopy
- diffraction
- refraction
- the nature of lenses
- phase contrast
- darkfield
- fluorescence microscopy
- live cell imaging and analysis
- positron emission tomography
- single-photon emission computed tomography
- nuclear magnetic resonance imaging
- ultrasound
- optical imaging
- stereology
- live cell and whole animal imaging techniques and their applications in diagnostic pathology, among others.
Course coordinator
lmp.grad@utoronto.ca for administrative queries.
Timings and location
This course is offered in odd years (i.e. years ending in 1,3, etc.) in the Winter session.
Tuesdays 10 am - 12 pm
Location: See schedule below.
Evaluation methods
60% Participation in lectures and laboratory sessions
40% Grant proposal and pitch deck presentation
Schedule
Download the full schedule and talk details (PDF).
|
Date and location |
Topic |
Lecturer/instructor |
|---|---|---|
|
January 21, 2025 MaRS, Princess Margaret Cancer Research Tower (PMCRT), 101 College Street. Room 13-710 |
10 - 11 am: Course Overview and Proposal Guidelines; Overview of Imaging Technologies (Sima Salahshor) 11 am - 12 pm: Optical Micro-Imaging and Image Analysis (James Jonkman) |
Dr. Sima Salahshor, Adjunct Professor at the University of Toronto, Department of Laboratory Medicine and Pathobiology (LMP), Principal at Shiruy Advisory James Jonkman, Scientist at University Health Network (UHN) and The Advanced Optical Microscopy Facility (AOMF) at MaRS Discovery District (MaRS DD) |
|
January 28, 2025 University College, 15 King's College Circle. Room 87 |
10 - 11 am: Business Strategies in the AI and Life Sciences Industry (Atoussa Mahmoudpour) 11 am - 12 pm: Communicating with Confidence and Clarity (Andrea Wojnicki) |
Atoussa Mahmoudpour, National Chair, Life Sciences & Technology and Partner at Cozen O'Connor Dr. Andrea Wojnicki, Executive communication coach, podcaster, and brand strategist at TalkAboutTalk and Columnist at Inc. Magazine |
|
February 4, 2025 Medical Sciences Building, 1 King's College Circle. Room 2394 |
10 - 11 am: Clinical Applications of AI in Digital Pathology (Minalini Lakshman and Matthew Hanna) 11 am - 12 pm: From one to many - How multiplex immunostaining, and new techniques in spatial transcriptomics and spatial metabolomics enhance the biological information obtained from tissue-based imaging (Trevor McKee) |
Dr. Minalini Lakshman, Executive-in-Residence at Brampton Venture Zone by TMU, Advisor and Consultant, MYK Solution, Inc., and Digital Pathology Association (DPA) Dr. Matthew Hanna, Vice Chair of Pathology Informatics and Associate Professor of Pathology, University of Pittsburgh Dr. Trevor McKee, Adjunct Lecturer at UofT Department of Laboratory Medicine and Pathobiology, CEO, Pathomics and CSO, BioCache™ Lab Solutions
|
|
February 11, 2025 Peter Gilgan Centre for Research and Learning (PGRL), 686 Bay St. Room 6-9621 |
10 - 12 pm: Principle of Scanning (SEM) and Transmission Electron Microscopy (TEM) |
Dr. Ali Darbandi, Scientist at SickKids Hospital, 3D Scanning Electron Microscopy (3D SEM) and CMDM; Cellular and Molecular Electron Microscopy facilities (CMDM) at Peter Gilgan Centre for Research & Learning (PGCRL) |
|
February 18, 2025 Medical Sciences Building, University of Toronto, 1 King’s College Circle. Room 3281 (10 am), Meeting location and introduction. Room 3214, Centre for Optophysiology (CfO), tour and demos |
10 - 12 pm: Application of Two-Photon and STED Super-Resolution Microscopy for Cellular Imaging and Optophysiology Imaging Facility Tour |
Dr. Kenichi Okamoto, Senior Scientist at Lunenfeld-Tanenbaum Research Institute (LTRI), Mount Sinai Hospital (MSH), Joseph and Wolf Lebovic Health Complex, Assistant Professor, Department of Molecular Genetics at U of T Dr. John Georgiou, Scientist at Lunenfeld-Tanenbaum Research Institute, Sinai Health, The Centre for Optophysiology (CFO) Dr. Thomas Sanderson, Scientist at The Centre for Optophysiology (CFO), Lunenfeld-Tanenbaum Research Institute |
|
February 25, 2025 Medical Sciences Building, 1 King's College Circle. Room 2394 |
Review of Proposals and Presentations for Pitch Decks |