Undergraduate courses

Course code description coordinator(s) term
LMP200H1

Pathobiology of the Cell [24L/12T] 

This course builds on concepts in cellular pathobiology to develop an advanced understanding of the function and dynamics of the cell in the context of health and disease. 

Jeffrey Lee 

Doug Templeton 

Winter
LMP299Y1

Research Opportunities Program 

A self-contained research project for 2nd year students to be completed under the supervision of an LMP faculty member. This program is administered by the A&S ROP office. Students select and apply for approved projects posted through CLNx. 

N/A Fall/Winter 
LMP301H1

Introduction to the Biochemistry of Human Disease [24L]

This course introduces concepts and mechanisms of disease processes as they arise from disturbances of normal biochemical and physiological functions. 

Lianna Kyriakopoulou 

Lusia Sepiashvili 

Winter
LMP305Y1

Pathobiology Research Analysis and Project [24L/100P] 

Offered starting in 2022-2023  

This course is designed to introduce third-year students to biomedical research, and to provide them with the analytical skills required to be a successful scientist. Students will also have the opportunity to carry out a full-year research project under the supervision of an LMP faculty member. 

Jeffrey Lee 

Stephen Smith 

Fall/Winter 
LMP310H1

Foundations of Pathobiology [24L/12T] 

Offered starting in 2022-2023 

This course covers the major molecular mechanisms that impact human health and disease. Specifically, it is divided into three blocks that focus on the fundamentals of pathobiology in cancer, cardiovascular diseases and infection. 

Myron Cybulsky 

Felix Leung 

Sonya MacParland 

Fall
LMP320H1

Pathobiology of Stem Cells [24L/12T] 

Offered starting in 2022-2023 

This course introduces stem cells and their impact on human health and disease. Stem cells are studied from the perspective of development and disease, with a focus on the nervous system, respiratory system, and cancer. 

Sunit Das 

Amy Wong 

Scott Yuzwa 

Winter
LMP330H1

Genetic and Computational Modeling in Human Development and Disease [24L/12T] 

Offered starting in 2022-2023 

This course introduces the use and impact of genetic model systems and organisms in exploring aspects of human reproduction, development, aging and disease. Ethical issues in animal research, genetic manipulation, and disease modeling are highlighted.  

This course also introduces the bioinformatics concepts and methods used in biological data analysis. 

David Irwin 

Karim Mekhail 

Bo Wang 

Fall
LMP340H1

Introduction to Pathobiology I [24L/12T]

This course covers concepts in pathogenesis, cell injury, adaptation and death, oxidative stress, ion channels and pumps, and calcium homeostasis. Molecular basis of diseases affecting iron, blood, and the cardiovascular system are also covered. 

Doug Templeton  Fall
LMP350H1

Introduction to Pathobiology II [24L/12T]

This course covers the molecular basis of tissue repair and fibrosis, endocrine and signaling disorders, introduction to neurodegenerative diseases, and mechanisms infection by virus, bacteria and parasites. 

Doug Templeton 

Winter

LMP363H1

Principles of Pathobiology [24L] 

This course covers the pathological changes brought on by foreign compounds; mechanisms of pathologic, toxic and carcinogenic change. 

Adriana Krizova  Fall
LMP365H1

Neoplasia [24L] 

A general introduction to the cellular and molecular aspects of cancer and its etiology. Pathophysiology of cancer, invasion and metastases, role of the immune system. 

Harry Elsholtz  Winter
LMP399Y1 

Research Opportunities Program

A self-contained research project for 3rd year students to be completed under the supervision of an LMP faculty member. This program is administered by the A&S ROP office. Students select and apply for approved projects posted through CLNx. 

N/A Fall/Winter 
LMP402H1

Inflammation and Infection [24L]

This course covers the mechanisms that allow microbial pathogens to cause disease and the host to detect infection, mount an inflammatory response, and resolve the infection.  

Myron Cybulsky 

Jeremy Mogridge 

Fall
LMP405Y1

Project in Pathobiology [154P]

A self-contained research project for 3rd and 4th year students to be completed under the supervision of an LMP faculty member. 

Michal Opas  Fall/Winter 
LMP406H1

Pathobiology of the Cardiovascular System [24L]

This course covers the pathobiology of the heart, blood vessels, and lymphatic system. Congenital diseases of the heart, ischemic injury, stroke. Treatments of vascular disease and cardiovascular biomaterials. Major focus on atherosclerosis and hypertension. The emphasis is on the underlying cell biology of these processes. 

Jason Fish  Winter
LMP408H1

Genetic Modeling of Human Development and Disease [24L]

This course introduces the use of genetic model systems and organisms in exploring aspects of human reproduction, development and disease. Ethical issues in animal research, genetic manipulation, and disease modeling are highlighted. 

David Irwin  Fall
LMP410H1

Pathobiology of Neurodegenerative Diseases [24L]

This course covers the molecular basis of neurodegenerative diseases of the central nervous system, including Alzheimer’s disease, Parkinson’s disease, Amyotrophic Lateral Sclerosis, and Prion diseases. 

Gerold Schmitt-Ulms  Fall
LMP415H1

Forensic Pathobiology [24L]

A thematic review of the major scientific areas and research controversies in forensic medicine. Classical forensic medicine is critically analyzed with emphasis on experimental methods to resolve controversies. We also explore how the justice system utilizes medical and scientific data. 

Magdaleni Bellis 

Jayantha Herath 

Winter
LMP420H1

Cancer Pathogenesis [24L/12T] 

Offered starting in 2023-2024

A general introduction to the cellular and molecular aspects of cancer and its etiology. Topics include pathophysiology of cancer, invasion and metastases, role of the immune system, immune evasion, understanding biological targets, chemotherapeutic and immunotherapeutic agents and its mechanism of action, and resistance mechanisms of cancer. 

George Charames 

Paul Hamel 

Fall
LMP430H1

Metabolic Disorders [24L/12T] 

Offered starting in 2022-2023 

This is an advanced-level course that focuses on the pathobiology of metabolic disorders, whether inherited or acquired. It covers enzymatic pathways and diseases associated with fat/energy metabolism, dyslipidemia, dysglycemia, aminoacidopathies and lysosomal storage disorders. 

Hoon-Ki Sung 

Jennifer Taher 

Libin Yuan 

Winter
LMP436H1

Microbial Pathogenesis [36L]

The course focuses on host-microbial interaction and analyzes the mechanisms underlying innate immune defense against pathogens. 

Stephen Girardin  Winter
LMP440H1

Mechanisms in Host-Microbe Interactions [24L] 

Offered starting in 2022-2023 

Mechanisms that allow microbial pathogens to cause disease and the host to detect infection, mount an inflammatory response and resolve the infection.  Primary research articles are discussed. Topics include commensal and pathogenic bacteria, microbe recognition, programmed cell death, immunometabolism, inflammatory diseases. 

Stephen Girardin 

Jeremy Mogridge 

Winter
LMP450H1

Organogenesis in Health and Disease [24L/12T] 

Offered starting in 2022-2023 

This course introduces advanced topics in stem cell biology and focuses on the latest developments related to the use of stem cells in the design and generation of organoids and organs for use in research. The use of organogenesis within basic and clinical research settings will be highlighted with a focus on several human diseases. 

Michael Laflamme 

Shinichiro Ogawa 

Karun Singh 

Fall