The LMP Research Conference and Product Show (LMPRC) 2022
Find out what happened at the LMPRC 2022!
See who won awards and pictures from the day.
You can contact the LMPRC committee at firstname.lastname@example.org.
Information for attendees
Download the LMPRC app to access talk details, abstracts, manage your itinerary and chat with participants!
The agenda and your personal itinerary will be available in the conference app.
7:30 – 8:00 Breakfast and registration
8:00 – 8:15 Welcome address
Dr. Rita Kandel
8:20 – 9:20 Oral Presentations Session I
9:25 – 10:25 Poster Presentations Session I
Neuroscience and Cancer
Cancer, Cardiovascular and Infectious Disease
10:30 – 11:30 Concurrent Symposia
10:30 – 11:00 sessions
- Artificial Intelligence in Medicine: Dr. Taufik Valiante 'Epilepsy a window to brain mechanisms'
- Organ-on-a-chip - 3D Modeling of a Disease: Dr. Yimu Zhao 'Towards the physiological relevant heart-on-a-chip'
- Unconventional Substances and Diseases: Dr. Adam Shlien 'The early origins and evolution of childhood cancer '
11:00 – 11:30 sessions
- Artificial Intelligence in Medicine: Dr. Rahul Krishnan 'Learning representations of histopathological images with self-supervised learning'
- Organ-on-a-chip - 3D Modeling of a Disease: Dr. Eugenia Kumacheva 'Tumors-on-a-chip: a Model for Drug Screening and Personalized Cancer Therapies'
- Unconventional Substances and Diseases: Dakota Gustafson ' Cancer therapy-related cardiotoxicity: Is the vasculature at the heart of the matter?'
11:30 – 12:15 Lunch
12:20 – 13:20 Keynote Speaker
Dr. Sonya MacParland 'Behind The Mask: Mapping the Human Liver in Health and Disease with Single Cell Resolution'
13:25 – 14:25 Poster Presentations Session II
Molecular cell biology, AI in Healthcare and Translational Research
Anatomical Pathology, Clinical Chemistry, Medical Microbiology
14:30 – 15:30 Oral Presentations Session II
15:35 – 16:35 “Power Hour” Events
Career Panel: Exploring post-graduate opportunities
- Medicine: Dr. Eleanor Latta
- Academia: Dr. Kelsey Thu and Dr. Sonya MacParland
- Alumni: Dr. Shawn Veitch (Medical Communications Writer), Dr. Nisha Kanwar (Genome specialist)
Mentorship Speed Dating
- Professional schools, Academia, Academic Industry, Non-academic Industry, and more
Beyond the Scope: A High Power View of Pathologists’ Finances
- Speakers: Dr. Mullen, Dr. Djordjevic, Dr. Yoon (See their bios on the Speaker Bios page)
Are you approaching the completion of the training, or do you want to be prepared to smartly use your first pay cheque? Join us this afternoon for a topic that’s the second most challenging in pathology: financial planning. In this panel discussion from our own LMP-affiliated pathologists, we will discuss the fundamentals of financial well-being for new pathologists. Our speakers are at differing stages of their careers and will offer insights on the relevant financial know-how at transition to practice, mid-career pathology, and at seasoned-veteran career status. The discussion will touch on investments, debt management, housing, payment models, and much more. The session will be a fusion of sage tell-all, and questions and answers.
16:40 – 17:40 Awards and mixer
Talk details and speaker bios
You will hear from the following speakers at the conference.
Dr. Sonya MacParland
Scientist in the Ajmera Transplant Centre at Toronto General Hospital Research Institute, a Canada Research Chair Tier 2 in Liver Immunobiology, and an Associate Professor in the University of Toronto’s departments of Laboratory Medicine and Pathobiology and Immunology.
Talk title: Behind The Mask: Mapping the Human Liver in Health and Disease with Single Cell Resolution
If you were to build an artificial liver, what cells would you build it with? How can we harness the livers own immune cells to treat and prevent liver disease? This talk will discuss the complexities of the liver, the most regenerative organ in the human body. We will talk about the team effort to map the liver with single cell resolution and efforts to share this research open-access for scientists around the world. We will also talk about how we can apply these maps to understand liver diseases that lead to liver transplantation.
AI in Medicine session
Dr. Taufik Valiante
Associate Professor of Surgery, University of Toronto and Staff Neurosurgeon and Surgeon Scientist at University Health Network
Talk title: Epilepsy a window to brain mechanisms
Dr. Rahul Krishnan
Assistant Professor of Computer Science and Medicine (Laboratory Medicine and Pathobiology), University of Toronto
Talk title: Learning representations of histopathological images with self-supervised learning
Vision Transformers (ViTs) and their multi-scale and hierarchical variations have been successful at capturing image representations, but their use has been generally studied for low-resolution images. For gigapixel whole-slide imaging (WSI) in computational pathology, WSIs can be as large as 150000 x150000 pixels at 20x magnification and exhibit a hierarchical structure of visual tokens across varying resolutions: from small patch images capturing individual cells, to medium sized patches characterizing interactions within the tissue microenvironment. We introduce a new ViT architecture called the Hierarchical Image Pyramid Transformer (HIPT), which leverages the natural hierarchical structure inherent in WSIs using two levels of self-supervised learning to learn high-resolution image representations. HIPT is pre trained across 33 cancer types using 10,678 gigapixel WSIs. We benchmark HIPT representations on 9 slide-level tasks, and demonstrate that: 1) HIPT with hierarchical pretraining outperforms current state-of-the-art methods for cancer subtyping and survival prediction, 2) self-supervised ViTs are able to model important inductive biases about the hierarchical structure of phenotypes in the tumor microenvironment. Our work presents a new way to create representations for histopathological images that are useful for a broad swathe of tasks.
Dr. Yimu Zhao
Postdoctoral research scientist at the Department of Biomedical Engineering, University of Toronto.
Talk title: Towards the physiological relevant heart-on-a-chip
In our lab, we are focused on the development of heart-on-a-chip that is relevant to human physiology. We started with a simple element in the heart, i.e. muscle fiber, and further integrated with perfusable vessel structures. We incorporated electrical stimulation to encourage the tissue maturation that resembles the adult-like heart muscle, which facilitates the drug toxicity test and disease modeling.
Dr. Eugenia Kumacheva
Professor and Distinguished Professor of Chemistry, University of Toronto
Talk title: Tumors-on-a-chip: a Model for Drug Screening and Personalized Cancer Therapies
Compelling data demonstrate advantages of organ-on-a-chip models for drug screening and personalized medicine for therapeutic cancer treatment. Integration of organ-on-a-chip platforms with machine learning would enable accelerated screening of combination therapies. Will pharmaceutical, regulatory, and academic researchers adopt these new strategies into their laboratories, after making large investments in the way they carry out research at present? This is a conceptual challenge.
Unconventional Substances session
Dr. Adam Shlien
Associate Director, Translation Genetics in the Department of Paediatric Laboratory Medicine at the Hospital for Sick Children, and Scientist in the SickKids Research Institute and Associate Professor in the Department of Laboratory Medicine & Pathobiology, University of Toronto
Talk title: The early origins and evolution of childhood cancer
The talk discusses how genome-wide mutational signatures can be used to reveal the processes and etiology of childhood cancer as well as their changes at relapse.
Senior Scientist, Toronto General Hospital Research Institute, University Health Network, Associate Professor, Department of Laboratory Medicine & Pathobiology, University of Toronto, Tier II Canada Research Chair in Vascular Cell and Molecular Biology.
Talk title: Cancer therapy-related cardiotoxicity: Is the vasculature at the heart of the matter?
Cancer therapy can have damaging effects on the heart and in some individuals this can lead to heart failure. We currently have no way of identifying individuals at the greatest risk of cardiotoxicity. In this presentation we will look at novel biomarkers and mechanisms that point to endothelial dysfunction as being critically important for cancer therapy-related cardiotoxicity.
The Product Show
- 9 am - 5 pm
- Arcadian Studio
Several vendors will be available to speak to you. Please visit them during the conference.
- As a University of Toronto event, all attendees must wear a mask except when presenting in an oral plenary session, eating and/or drinking. We ask poster presenters to wear their masks when presenting.
- During lunch (from 11:30am – 12:15pm), we encourage you to take your boxed lunches and spread out across the venue, beyond the main ballroom and into the lofts and studio, and even outside, weather permitting – to encourage physical distancing.
- We will have masks at the registration desk if you need one.
- If you have access to a rapid test consider performing it before you come to the conference (night before or morning of). If the result is positive, please stay home.
- If you are presenting and cannot make it to the conference due to a positive test, email email@example.com and firstname.lastname@example.org as soon as possible to let them know.
Photography and videos
A professional photographer will be at the event and we will also be doing some video recordings for departmental purposes.
If you do not wish to be in any of the photos or videos, please make yourself known to the person taking pictures or videos.
Information for participants and presenters
Who should submit and abstract and how
You must have registered for the conference in addition to submitting an abstract.
It is compulsory for the following learners to submit an abstract:
- Second and fourth-year LMP research-graduate students
- Second-year Translational Research Program students (capstone project presentations)
- All postgraduate clinical trainees
Abstract submission and registration is now closed. If you have missed the deadline, please contact email@example.com.
Preparing for your poster presentation
Do you want help practicing your poster presentation? Contact the Peer Communication Team and access expert coaching and feedback on your presentation.
- Free Research Poster PowerPoint Templates from posterpresentations.com
- Scientific Poster PowerPoint Templates from Make Signs
- Free PowerPoint research poster templates in various sizes and styles from Genigraphics
And from the School of Graduate Studies
- Design of Scientific Posters, Michael Alley, Penn State University
- Advice on Designing Scientific Posters, Colin Purrington, Swarthmore College
- Poster Presentation Guidelines, Varinder K. Randhawa and Philip J. Bilan
- Creating Effective Poster Presentations, George R. Hess, Kathryn W. Tosney, and Leon H. Liegel
- Emily Foster
- Rupal Hatkar
- Maryam Khalil
- Negar Khosraviani
- Atefeh Mohammadi
- Kuganya Nirmalarajah
- Siobhan Wilson
- Youheng (Henry) Xie
- Jenni Bozec
- Nelson Cabral
- Ian Marquez
- Paula Nixon
- Emma Sanchez-Swaren
- Brandon Wells