Over 350 LMP faculty members take part in a broad spectrum of research at state-of-the-art facilities across Toronto.

Our diverse research encompasses all organ systems and is enabled by a wide variety of techniques ranging from world-class discovery and mechanistic research to key areas of translational research — including biomarkers, biobanking, quality, and informatics.

We foster collaborations within the department and encourage basic and clinical scientists to translate their research into new discoveries and potential treatments. 

As an academic department, LMP emphasizes the creation and communication of knowledge, focusing on the causes and mechanisms of disease, translating knowledge into improved medical practice and health outcomes, and informing health policy. 

LMP Investigators cover a wide spectrum of research aimed at understanding the causes and mechanisms of human disease. 

The term “Pathobiology” encompasses: 

  • Pathology – the nature of changes produced by disease. 
  • Pathogenesis – the mechanisms and changes in disease that occur at the molecular, cellular and tissue level. 
  • Pathophysiology – the changes in organ and systems function that accompany disease. 

In this context, pathophysiology is very important, as disease is often underpinned by normal physiologic mechanisms that have gone awry; therefore we emphasize the importance of studying the full spectrum of normal development and tissue function. 


Brain and Neuroscience

Our researchers study neuropyschology, neuroimmunology, neurogenetics, proteomics, and neurological disease mechanisms.


To improve cancer treatment and reduce the burden of this disease, our researchers strive to expand their understanding of cancer biology.


Our researchers study the influence of hemodynamics, inflammatory and thrombotic mechanisms in atherosclerosis.

Genetics, Genomics and Proteomics

From the identification of genetic mutations underlying disease, to the development of prognostic technologies that impact health care delivery.


Our researchers investigate the nature of disease of the hematopoietic system and related organs.

Human development and aging

In the hopes of discovering interventions that promote health and longevity, our researchers study the molecular and physiological changes that occur during the developmental and aging process.

Infectious diseases and Immunopathology

Our researchers use a variety of leading-edge microbiological, biochemical, immunological, and biophysical techniques to discover important model principles of microbial pathogenesis.

Metabolism and nutrition

Our researchers study the mechanisms in diabetes, endocrine function and dyslipidemias.

Molecular and cell biology

Researchers involved in Molecular and cellular biology decipher an incredibly wide array of molecular and cellular processes.
Jan 25 The highs and lows of enteric infections
Monday seminar series | 4:00pm–5:00pm
Jan 28 Research connections: COVID-19 series (A SickKids Research Institute seminar series)
Workshop/Seminar | 12:00pm–1:00pm
Feb 1 Understanding pediatric sarcomas – a 15 year journey
Monday seminar series | 4:00pm–5:00pm
Feb 2 Drug Regulatory Pathways (A TR Talk)
TR Talks (Translational Research) | 5:00pm–7:00pm
Feb 8 Cardiovascular applications of human pluripotent stem cells: the new patient?
Monday seminar series | 10:00am–11:00am