Making Sense of Senescence: Aging Through a Microscopic and Macroscopic Lens
11th LMPSU conference
Dr. Marc Grynpas
Professor, Department of Laboratory Medicine & Pathobiology, University of Toronto
Speaking 1:30 pm: How conjugated drugs can regenerate bone
Marc Grynpas, PhD, is a professor in the Department of Laboratory Medicine and Pathobiology and a member of the Institute for Biomedical Engineering at the University of Toronto. He is also a Senior Scientist at the Lunenfeld-Tanenbaum Research Institute of Mount Sinai Hospital. He is the Director of the Bone and Mineral Research Group at the University of Toronto.
Dr. Grynpas graduated from the Free University of Brussels with an undergraduate degree in Physics. At the University of London, he completed his Ph.D. in Crystallography and Biophysics on the structure of bone. After a post-doctoral fellowship at Queen Mary College (University of London) on the relationship between bone structure and bone mechanical properties, he joined the laboratory of Professor Melvin Glimcher at the Children’s Hospital in Boston (Harvard Medical School) where he worked on the nature of the bone mineral.
His research laboratory is located at The Lunenfeld-Tanenbaum Research Institute of Mount Sinai Hospital in Toronto. He has published over 260 refereed papers, 26 book chapters, and proceedings and is currently holding 5 patents.
Dr. Marc Grynpas’ research focuses on the structure, chemistry, and biology of the skeleton. His work covers basic research on biological mineralization to translational research on bone fragility in osteoporosis. More specifically, he is trying to understand the mechanisms, which lead to bone fragility in osteoporosis and joint degeneration in arthritis. Using animal models, he is investigating the determinants of bone quality. He is also working together with colleagues on new biomaterials and conjugated drugs to regenerate bone.