LMP301H1 - Introduction to the Biochemistry of Human Disease
Course description
This course introduces concepts and mechanisms of disease processes as they arise from disturbances of normal biochemical and physiological functions.
The rational use of the clinical biochemistry laboratory in the diagnosis and management of disease is explained.
Not intended for students in the Pathobiology Specialist program.
Course coordinator
Hospital for Sick Children, 555 University Ave., Room S102 Elm Wing
lianna.kyriakopoulou@sickkids.ca
Hospital for Sick Children, 555 University Ave., Room 3606 Atrium
Teaching assistant
Justin Meade
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Term |
Winter 2023 |
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Class location and time |
Tuesday 12 - 1 pm: MS 2173, Medical Sciences Building, 1 King’s College Circle. With the exception for Feb. 28 class will be in MS 3278. Thursday 12 - 1 pm: HS 610, Health Sciences Building, 155 College St. |
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Office hours |
Thursday 1 - 2 pm HS 610, Health Sciences Building, 155 College St. |
Course details
- Hours: 24L
- Prerequisite: BCH210H1/ BCH242Y1
- Exclusions: LMP310H1 and LMP320H1
- Distribution requirements: Science
- Breadth requirement: Living Things and Their Environment (4)
- Enrolment limits: 210 students
Student evaluation
In-class mid-term 1: 25%
In-class mid-term 2: 25%
Final exam: 50%
See information on Academic Integrity
Schedule
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Date |
Title |
Instructor |
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January 10, 2023 |
Introduction to human disease |
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January 12, 2023 |
Laboratory tests and interpretation |
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January 17, 2023 |
Introduction to cases |
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January 19, 2023 |
Water and electrolytes |
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January 24, 2023 |
Acid-Base disorders |
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January 26, 2023 |
Renal disease |
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January 31, 2023 |
Lipids and cardiac disease |
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February 2, 2023 |
Liver Disease and Office Hour |
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February 7, 2023 |
Viral hepatitis |
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February 9, 2023 |
First Mid-term Exam (Covers Lectures 1-7) |
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February 14 2023 |
Introduction to endocrine diseases |
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February 16, 2023 |
Thyroid disease |
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February 20, 2023 |
Reading Week |
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February 28, 2023 |
Adrenal disease |
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March 2, 2023 |
Calcium, Vitamin D and Parathyroid |
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March 7, 2023 |
Infertility |
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March 9, 2023 |
Diabetes and Office Hour |
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March 14, 2023 |
Iron and heme |
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March 16, 2023 |
Cancer markers |
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March 21, 2023 |
Second Mid-term Exam (covers lectures 8 - 15) |
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March 23, 2023 |
Newborn screening |
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March 28, 2023 |
Pregnancy |
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March 28, 2023 |
Supplemental Exam |
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March 30, 2023 |
Clinical toxicology |
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April 4, 2023 |
Therapeutic drug monitoring & Personalized medicine |
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April 6, 2023 |
Molecular diagnostics and Office Hour |
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TBC |
Final Exam (covers lectures 1-22) |
Recommended readings or text book
“Clinical Biochemistry 5th edition” by A. Gaw, M.J. Murphy, R. Srivastava, R.A. Cowan, and D.St.J. O’Reilly, published by Churchill Livingston, 2013.