How does the heart and vascular system develop and how do these systems respond to physical and biochemical stresses during disease development?
Our researchers answer these pivotal questions by studying the influence of hemodynamics, inflammatory and thrombotic mechanisms in atherosclerosis.
They also investigate the remodelling of the extracellular matrix and signalling between cells and matrix in vascular disease.
Research is conducted at the molecular, cellular, organ, and organism level using models ranging from zebrafish to mice and, ultimately, to humans.
We foster collaborations within the department and encourage basic and clinical scientists to translate their research into new discoveries and potential treatments.