Molecular Pathology for Surgical Pathologists community of interest
Here we post videos and any resources from previous events held by the Office of Continuing Professional Development (CPD) at LMP for the Molecular Pathology for Surgical Pathologists Community of Interest group.
All Pathologists, Pathology Fellows, and clinical scientists with an interest in Molecular Pathology are invited and welcome to these events.
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These meetings are usually organised by Dr. Elan Hahn.
An introduction to molecular pathology for surgical pathologists
In summer 2025, we ran a mini educational series to cover the basics of molecular pathology for practicing pathologists.
The learning objectives are to:
- understand clinical molecular reports
- integrate molecular results into their surgical pathology interpretations
- map the workflow in molecular pathology from specimen handling through sequencing, bioinformatics, interpretation and reporting
- select the most suitable molecular assay for a given clinical question
- understand common preanalytical factors that can impact molecular testing.
This series can be accessed for free below.
All sessions are run by Dr. Elan Hahn and Dr. Yael Fisher.
Session 1: Introduction, July 15, 2025
Learn how to define key terms in molecular pathology and write genomic and protein-level changes using correct HGVS syntax.
Session 2: Sequencing techniques and laboratory workflow, July 22, 2025
Learn how to compare different methods used in molecular pathology, including their limitations and applications; identify, prevent, and troubleshoot preanalytical factors that can compromise sequencing quality; outline the laboratory workflow of next-generation sequencing; and describe the differences between commercial and custom-made NGS panels.
Session 3: Bioinformatics, July 29, 2025
Learn how to recognize the different types of output files and describe their purpose; summarise the bioinformatic pipeline; utilize Integrative Genomics Viewer (IGV) to visualize and verify variants; and understand the rationale behind using tier-based variant classification schemes.
Session 4: Interpretation, August 5, 2025
Learn how to classify common somatic variants by oncogenicity and actionability schemes; navigate and utilize publicly available databases for understanding somatic variant classification; and request molecular tests according to the CCO coverage and requirements.