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LMP1212H: Contributions of Neuropathology and Artificial Intelligence in understanding neurogenerative disorders

Who can attend

You must be registered in a graduate program at the University of Toronto to attend this course.

This course is open to all graduate students at the University of Toronto, provided you have pre-approval from your department and the course coordinators. 

Course description

This course provides an introduction to neuropathology and artificial intelligence (AI) in the context of neurodegenerative disorders.

Post-mortem neuropathological examination remains the gold-standard for diagnosis and further provides neuropathological characterization of neurodegenerative disorders.

Understanding the pathological changes can be fundamental to developing biomarkers, identifying effective therapeutic targets and developing accurate disease-models.

As digital pathology and AI-based evaluation methods continue to advance, it is essential to explore the different applications of AI in neurodegenerative disorders. This includes investigating the selection of AI-based models that have been used in the literature, its prediction or classification accuracy, its advantages and limitations, and possible ethical considerations.

This course encourages collaborative learning and by the end of the course, students will have gained comprehensive knowledge on how neuropathology and AI can refine understanding of neurodegenerative disorders. This course will prepare students for research in neurodegenerative disorders and promote interdisciplinary collaborations.

Course coordinators

Dr. Gabor Kovacs

Dr. Shelley L. Forrest

Dr. Ain Kim

lmp.grad@utoronto.ca for administrative queries.

Timings and location

This course is offered every year in the Fall term.

Wednesdays, 11:00 am - 1:00 pm.

Location: In person, MS 4279

Evaluation methods

  • Final exam (40%)
  • Weekly post-lecture assignment (30%)
  • Participation and discussion (30%)

Schedule

Date

Topic

Instructor

October 1, 2025

Introduction to neurodegenerative diseases: current concepts

Dr. Gabor Kovacs

October 8, 2025

Introduction to brain anatomy

Dr. Shelley L. Forrest

October 15, 2025

PrP proteinopathies

Dr. Gabor Kovacs

October 22, 2025

Synucleinopathies

Dr. Gabor Kovacs

October 29, 2025

Tauopathies

Dr. Shelley L. Forrest

November 5, 2025

TDP-43 and FUS/FET proteinopathies

Dr. Shelley L. Forrest

November 12, 2025

Alzheimer’s disease and cerebral amyloidosis Reading week

Dr. Gabor Kovacs

November 19, 2025

Cerebrovascular diseases: relevance for dementia and movement disorders

Dr. Gabor Kovacs

November 26, 2025

Neuropathology microscopy 

Dr. Shelley L. Forrest

December 3, 2025

Basics of Artificial Intelligence

Dr. Ain Kim

December 10, 2025

Applications and future trends of Artificial Intelligence in Neuropathology

Dr. Ain Kim

TBD

Final Exam

Dr. Ain Kim