Assistant Professor

Lina Chen

Department of Laboratory Medicine & Pathobiology

MD, MSc, MMed, FRCPC

Location
Sunnybrook Health Science Centre
Address
Laboratory Medicine and Molecular Diagnostics, 2075 Bayview Avenue, Toronto, Ontario Canada M4N 3M5
Research Interests
Artificial Intelligence, Cancer, Infectious Diseases & Immunopathology
Clinical Interests
Pathology: Liver, Pathology: Gastrointestinal
Appointment Status
Primary

Recent Publications

Tang S, Hosseini M.S, Chen L, Varma S, Rowsell C, Damaskinos S, Plataniotis K, & Wang Z. Probeable DARTS with Application to Computational Pathology. ArXiv, (2021). abs/2108.06859.

Chenard S, Jackson C, Vidotto T, Chen L, Hardy C, Jamaspishvilli T, Berman D, Siemens RD, Koti M. Sexual dimorphism in outcomes of non-muscle invasive bladder cancer: a role of CD163+ macrophages, B cells and PD-L1 immune checkpoint. Eur Urol Open Sci. 2021 Jun 3;29:50-58. doi: 10.1016/j.euros.2021.05.002.

Chiu M, Garabon J, Chen L, Karp N, Kapoor A, Woolfson JP. Mevalonic aciduria associated with intrahepatic bile duct paucity. Hepatology. 2021 Feb 27. doi: 10.1002/hep.31778.

Chen L, Hurlbut D, Bechara R, Varma S. Whole-circumference endoscopic submucosal dissection specimens: “Rolling out” a new specimen preparation technique. Canadian Journal of Pathology (2021), Vol. 13 Issue 1, p33-40. 8p.

Chen L, Orr C, Wang T. Prevalence of histological features resembling autoimmune pancreatitis in pancreas resection specimens. Histopathology (2020) 77, 673– 677.

Bechara R, Chen L, Chung W, Varma S. Salvage circumferential endoscopic submucosal dissection for refractory dysplastic Barrett’s esophagus. VideoGIE. 2020 Aug.07.005.

Chen L, Li Y, Tyryshkin K, Deng L, Scott D, Rauh M, Crocker S, Baetz T, LeBrun D. Objective quantification of BCL2 protein by multiplex immunofluorescence in routine biopsy samples of diffuse large B-cell lymphoma demonstrates associations with survival and BCL2 gene alterations. Leuk Lymphoma. 2020 Jan 16:1-11.

Schwenger KJP, Chen L, Chelliah A, Da Silva HE, Teterina A, Comelli EM, Taibi A, Arendt BM, Fischer S, Allard JP. Markers of activated inflammatory cells are associated with disease severity and gut dysbiosis in adults with non-alcoholic fatty liver disease. International Journal of Molecular Medicine. Int J Mol Med. 2018 Oct;42(4):2229-2237.

Troshchynsky A, Dzneladze I, Chen L, Sheng Y, SaridakisV, Wu GE. Functional analyses of polymorphic variants of human terminal deoxynucleotidyl transferase. Genes Immun. 2015 Sep;16(6):388-98.

Chen L, Duvvuri B, Grigull J, Jamnik R, Wither JE, Wu GE. Experimental evidence that mutated-self peptides derived from mitochondrial DNA somatic mutations have the potential to trigger autoimmunity. Hum Immunol. 2014 Aug;75(8):873-9.

Duvvuri B, Duvvuri VR, Wang C, Chen L, Wagar LE, Jamnik V, Wu J, Grigull J, Watts TH, Wu GE. The human immune system recognizes neopeptides derived from mitochondrial DNA deletions. J Immunol. 2014 May 15;192(10):4581-91.