Case of the Month: October 2026
Clinical history
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47-year-old right-handed woman
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First seizure four years ago
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Left frontal lobe mass found the same year
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Seizures recently more frequent
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MRI now: 5 cm mass with patchy enhancement and new hemorrhage
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Awake craniotomy with language mapping, tumour resected
Large heterogeneous mass in the left frontal lobe
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Intra-axial, about 5 cm in each dimension
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Patchy enhancement in part of the lesion
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New hemorrhage with a fluid-fluid level
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FLAIR hyperintensity around the lesion
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2 mm midline shift, no other lesions
Questions:
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What is the differential diagnosis for this mass?
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Which features do you see on H&E?
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What is the diagnosis, and which tests confirm it?
How to participate
Take a look at the images.
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Join the Special Interest Group in Laboratory Medicine to learn more about Laboratory Medicine.
Laboratory Medicine and the study of disease for medical students
