Assistant Professor

Shamini Selvarajah

Department of Laboratory Medicine & Pathobiology - Cytogenetics

Hon.BSc, PhD, DABMGG, FACMG, FCCMG

Location
Toronto General Hospital: University Health Network (UHN)
Address
200 Elizabeth St., Lab Medicine Program, 11th Floor, Room. 11NU1161, Toronto, Ontario Canada M5G 2C4
Research Interests
Cancer, Genetics Genomics & Proteomics
Clinical Interests
Molecular Genetics, Cytogenetics
Appointment Status
Primary

Professional Memberships

  • Member, Cancer Genomics Consortium (CGC)
  • Member, ClinGen Consortium
  • Fellow, Canadian College of Medical Geneticists (CCMG)
  • Member, Association for Molecular Pathology (AMP)
  • Fellow, American College of Medical Genetics and Genomics (Membership ID 08709)
  • Diplomate, American Board of Medical Genetics and Genomics

Dr. Shamini Selvarajah is an Assistant Professor in the University of Toronto’s Department of Laboratory Medicine and Pathobiology, and an ABMGG and CCMG dual-boarded diagnostic laboratory scientist in the Division of Genome Diagnostics at the University of Health Network.

She attained her PhD at the University of Toronto, and underwent training in molecular cytogenetics at the Harvard Medical School Genetics Training Program and clinical molecular genetics at McMaster University.

Her role as a clinical lab scientist includes oversight of genetic testing for oncology, including companion diagnostics, genomic test development for clinical laboratory use, and applications of NGS in clinical care.

Research Synopsis

My translational research interests are focused on genitourinary cancer genomics, as well as the development and implementation of non-invasive genomic tests.

Selected Publications

Selvarajah S, Schrader KA, Kolinsky MP, Rendon RA, El Hallani S, Fleshner NE, Hotte SJ, Lorentz J, Panabaker K, Perrier R, Pouliot F, Spatz A, Yip S, Chi KN. Recommendations for the implementation of genetic testing for metastatic prostate cancer patients in Canada. Can Urol Assoc J. 2022 Oct;16(10):321-332. Principal Author.

Yip SM, Morash C, Kolinsky MP, Kapoor A, Ong M, Selvarajah S, Nuk J, Compton K, Pouliot F, Lavallée LT, Khalaf DJ, Hamilton RJ, Gotto GT, Rendon RA, Antebi E, Hotte SJ, Malone S, Chi KN, Drachenberg DE, Saad F, Chan J, Ferrario C, Ko J, Shayegan B, Parimi S, So AI, Feifer A, Jansz K, Finch D, Chin JL, Osborne B, Ho KF, Galamo CD, Zardan A, Niazi T. Genetic testing practices among specialist physicians who treat prostate cancer A Canadian, cross-sectional survey. Can Urol Assoc J. 2023 Oct;17(10):326-336. doi: 10.5489/cuaj.8403. Co-author.

Prendeville S, Kaur H, Ansari S, Alqaqa S, Stockley TS, Lajkosz K, van der Kwast T, Cheung CC, Selvarajah S. Somatic Tumor Testing in Prostate Cancer: Experience of a Tertiary-Care Center Including Pathologist-Driven Reflex Testing of Localized Tumors at Diagnosis. Modern Pathology. 2024 June: 37(6): 100489. Impact Factor: 7.5. Corresponding author.

Appointments

Clinical Molecular Geneticist and Clinical Cytogeneticist, Division of Genome Diagnostics, Laboratory Medicine Program, University Health Network, Toronto, Ontario, Canada (2019 - present)

Clinical Investigator, Princess Margaret Cancer Centre Research Institute, University Health Network, Toronto, Ontario, Canada (2019 - present)

Assistant Professor, Department of Laboratory Medicine and Pathology, University of Toronto, Toronto, Ontario, Canada (2017 - present)