Assistant Professor

Jiong Yan

Department of Laboratory Medicine & Pathobiology - Hematological Pathology


Toronto General Hospital: University Health Network (UHN)
200 Elizabeth St., Lab Medicine Program, Eaton Wing 11th Floor, Toronto, Ontario Canada M5G 2C4
Research Interests
Cancer, Hematopathology
Clinical Interests
Pathology: Hematological
Appointment Status

I obtained my doctoral degree in Medicine in Peking Union Medical College in China and received my PhD and post-doctoral training in molecular and human Genetics at Baylor College of Medicine. My Pathology residency and Hematopathology fellowship training was at New York-Presbyterian Hospital/Weill Cornell Medical Center. I have published more than 20 peer-reviewed papers in reputed journals. I worked as an assistant professor in the Department of Pathology and Laboratory Medicine at the University of Saskatchewan and I am currently a hematopathologist in the department of Laboratory Medicine and Pathobiology.   


Research Synopsis


My research interests are molecular mechanisms of hematopoietic neoplasms.   I am interested in characterizing morphologic, immunophenotypic, and molecular features of different types of  hematopoietic neoplasms as well as their relevance to clinical treatment and outcome.     


Recent Publications


Cunningham CE, Li S, Vizeacoumar FS, Bhanumathy KK, Lee JS, Parameswaran S, Furber L, Abuhussein O, Paul JM, McDonald M, Templeton SD, Shukla H, El Zawily AM, Boyd F, Alli N, Mousseau DD, Geyer R, Bonham K, Anderson DH, Yan J, Yu-Lee LY, Weaver BA, Uppalapati M, Ruppin E, Sablina A, Freywald A, Vizeacoumar FJ. 2016. Therapeutic relevance of the protein phosphatase 2A in cancer. Oncotarget. doi: 10.18632/oncotarget.11399.

Zhang T, Ma J, Nie K, Yan J, Liu Y, Bacchi CE, Queiroga EM, Gualco G, Sample JT, Orazi A, Knowles DM, Tam W. 2014. Hypermethylation of the tumor suppressor gene PRDM1/Blimp-1 supports a pathogenetic role in EBV-positive Burkitt lymphoma. Blood Cancer J. 4:e261. doi: 10.1038/bcj.2014.75.

Hasserjian RP, Campigotto F, Klepeis V, Fu B, Wang SA, Bueso-Ramos C, Cascio MJ, Rogers HJ, Hsi ED, Soderquist C, Bagg A, Yan J, Ochs R, Orazi A, Moore F, Mahmoud A, George TI, Foucar K, Odem J, Booth C, Morice W, DeAngelo DJ, Steensma D, Stone RM, Neuberg D, Arber DA. 2014. De novo acute myeloid leukemia with 20-29% blasts is less aggressive than acute myeloid leukemia with ≥30% blasts in older adults: a Bone Marrow Pathology Group study. Am J. Hematol. 89:E193-199.

Yan J, Nie K, Mathew S, Tam Y, Cheng S, Knowles DM, Orazi A, Tam W. 2014. Inactivation of BANK1 in a novel IGH-associated translocation t(4;14)(q24;q32) suggests a tumor suppressor role in B-cell lymphoma. Blood Cancer J. 4:e215. doi: 10.1038/bcj.2014.36.

Lacaria M, Saha P,  Potocki L, Bi W, Yan J, Girirajan S, Burns B, Elsea S, Walz K, Chan L,  Lupski JR, Gu W. 2012. A duplication CNV that conveys traits reciprocal to metabolic syndrome and protects against diet induced obesity in mouse and human. PLoS Genet. 8(5):e1002713.

Schuetz AN, Pisapia D, Yan J, Hoda RS. 2012. An atypical morphologic presentation of Coccidioides spp. in fine-needle aspiration of lung. Diagn Cytopathol. 40:163-167.