Associate Professor

Julia Keith

Department of Laboratory Medicine & Pathobiology - Neuropathology

MD, FRCPC

Location
Sunnybrook Health Science Centre
Address
2075 Bayview Ave., Department of Anat Pathology, E432, Toronto, Ontario Canada M4N 3M5
Research Interests
Brain & Neuroscience
Clinical Interests
Pathology: Neuropathology
Appointment Status
Primary
Accepting
Accepting medical students for shadowing

Research Synopsis

My academic interests include education, neuromuscular and neurodegenerative neuropathology.

Selected Publications

Keith JL, Bilbao J, Croul S, Ang LC, Guiot MC, Rossiter J, Ghorab Z, Hawkins C, Karamchandani J. Clinical Neuropathology practice guide 6-2013: morphology and an appropriate immunohistochemical screening panel aid in the identification of synovial sarcoma by neuropathologists. Clin Neuropathol. 2013 Nov-Dec;32(6):461-70.

Keith J, Croul S, Ang LC, Bilbao J, Dickson B. Synovial sarcoma of the nervous system: a clinicopathologic study of 9 patients. Modern Pathology. 2013 25(S2): 131A-132A.

Keith J, Pirouzmand F, Diamandis P, Ghorab Z. Intra-operative cytodiagnosis of Progressive Multifocal Leukoencephalopathy.  Cytopathology. 2014 Feb;25(1):59-61.

Sahgal A, Ironside S, Perry J, Mainprize T, Keith J, Laperriere N, Tsao M, Paszat L. Factors influencing overall survival specific to adult low-grade astrocytoma (LGA): A population-based study. Clinical Oncology. 2013 Jul;25(7):394-9.

Orlov D, Keith J, Rosen D, Croul S, Kraeva N, Riazi S. Analysis of histomorphology in malignant hyperthermia-susceptible patients. Can J Anaesth. 2013 Oct;60(10):982-989.

Au K, Bilbao J, Mainprize T, Schwartz M, Keith J. Oligodendrogliomas with abundant Refractile Eosinophilic Granular Cells. Can J Neurol Sci. 2013 Sep;40(5):746-8.

Au K, Black SE, Bilbao JB, Masellis M, Keith J. FTLD: Updated Pathology and Co-Existing Neurodegenerative Phenomena in a Cohort of 52 Patients. Modern Pathology, In Press. 

Au K, Black SE, Masselis M, Bilbao JB, Keith J. Mesial temporal sclerosis in FTLD: an association with age, cerebrovascular disease and TDP43. Neurology, In Press. 

Mitchell S, Black SE, Rogaeva E, Bilbao J, Keith J. Co-existing glioneuronal tauopathy as a potential explanation for semantic variant primary progressive aphasia phenotype in FTLD-TDP43 harmonized type A. Neurology, In Press.

Xi Z, Zinman L, Moreno D, Schymick J, Liang Y, Sato C, Zheng Y, Ghani M, Dib S, Keith J, Robertson J, Rogaeva E. Hypermethylation of the CpG Island Near the G4C2 Repeat in ALS with a C9orf72 Expansion. Am J Hum Genet. 2013 May: S0002-9297(13)0017. 

Munoz D, Rogaeva E, Zinman L, Young B, Masellis M, Black S, Robertson J, Keith J, Bilbao J. Genetic, clinical and pathological associations of TDP43pathy with cerebellar p62 inclusions. J Neuropathol Exp Neurol 2012 71:547-600.

Gao F, Noor R, Keith J, Nadeau Y, Kiss A, Black SE. Relationship between collagenosis of the deep medullary veins and periventricular WMH on MRI in Alzheimer’s disease: Does one size fit all? Alzheimer’s & Dementia: The Journal of the Alzheimer’s Association. 2012 July 8(4Supplement): 297.  

Keith J, Fabian VA, Walsh P, Charles A, Robitaille Y. Neuropathological homology in true Galloway-Mowat syndrome. J Child Neurology 2011. 26(4): 510-7. 

Keith J, White J, Pascu O, Fabian VA. Fatal cerebellar hemorrhage following Australian brown snake envenomation.  Can J Neurol Sci. 2011 39 (1): 120-121. 

Keith J, Bilbao J, Baskind R. JC virus granular neuronopathy and rhombencephalic progressive multifocal leukoencephalopathy: case report and review of the literature. Neuropathology. 2011 10:1440-1789.

Keith J, Zinman L, Cohen S, Young B, Bilbao JM. Paraspinal myopathy with shard-like compact aggregates of thin filaments. Muscle Nerve. 2011 44(1):145-6.   

Keith J, Afshar-Ghotli Z, Roussev R, Ernst B, Young B, Bilbao JM. Myopathy as the initial manifestation of primary amyloidosis. Can J Neurol Sci. 2011. 38: 161-164. 

Xiao H, Sanelli T, Dib S, Sheps D, Findlater J, Keith J, Bilbao J, Zinman L, Rogaeva E, Robertson J. RNA targets of TDP-43 identified by UV-CLIP are deregulated in ALS. Mol Cell Neurosci. 2011. 47(3):167-80.

Meyer M, Keith J, Reddy H, Megyesi J, Hammond R. Examining Sources of Error in Neuropathology Frozen Section Diagnosis. Can J Neurol Sci. 2010 37: 620-624. 

Derry KL, Nicolle MN, Keith J, Hammond R. Percutaneous Muscle Biopsies: Review of 900 cases at LHSC. Can J Neurol Sci. 2009 36(2): 201-6. 

Keith J, Ang LC. PSP: a review of co-existing neurodegeneration. Can J Neurol Sci. 2008 35: 602-8.

Keith J, Ang LC. Progressive Supranuclear Palsy: clinicopathologic correlation between tau burden, co-existing neurodegeneration and cognitive status. Can J Neurol Sci. 2007 34: 501