Assistant Professor

Steven White

Department of Laboratory Medicine & Pathobiology

MD, PhD, MPH, DABP (AP & FP)

steven.m.white@utoronto.ca

Location

Ontario Forensic Pathology Service

Address

25 Morton Shulman Avenue, Toronto, Ontario Canada M3M 0B1

Research Interests

Cardiovascular, Metabolism & Nutrition

Clinical Interests

Pathology: Forensic, Pathology: Cardiovascular, Pathology: Autopsy

Appointment Status

Primary

You can follow Dr. White on:

LinkedIn: Steven White
Twitter (X): @swhitemdphd

Dr. Steven White is a forensic pathologist with the Ontario Forensic Pathology Service and is board-certified in Anatomic and Forensic Pathology by the American Board of Pathology. He obtained his undergraduate degree in Biology and a Master of Public Health degree in Epidemiology from Tulane University before entering the MD/PhD program at Louisiana State University School of Medicine in New Orleans.

His research focused on using embryonic stem cells to study development of specialized cardiac pacemaking and conducting cells.

After medical school, Dr. White completed residency training in Anatomic Pathology at the National Institutes of Health (NIH), followed by a fellowship in Forensic Pathology at the Cook County Medical Examiner’s Office in Chicago, where he worked as an Assistant Medical Examiner and Cardiovascular Pathology Consultant. He served on the faculties of Northwestern University and Rush University.

In 2019, Dr. White moved to Vancouver to help establish a Provincial forensic pathology service for the BC Coroners Service, overseeing a team of forensic pathologists and teaching medical students and pathology residents at the University of British Columbia.

Research synopsis

Dr. White’s research interests involve collaborating on projects related to cardiovascular pathology, genetics, metabolomics, and sudden, unexpected death in children and young adults.

Selected publications

Janzen ML, Davies B, Laksman ZWM, Roberts JD, Sanatani S, Steinberg C, Tadros R, Cadrin-Tourigny J, MacIntyre C, Atallah J, Fournier A, Green MS, Hamilton R, Khan HR, Kimber S, White S, Joza J, Makanjee B, Ilhan E, Lee D, Hansom S, Hadjis A, Arbour L, Leather R, Seifer C, Angaran P, Simpson CS, Healey JS, Gardner M, Talajic M, Krahn AD. Management of inherited arrhythmia syndromes: a HiRO consensus handbook on process of care. Canadian Journal of Cardiology (CJC Open), 2023; 5: 268-284; doi: 10.1016/j.cjco.2023.02.006.

Webster G, Puckelwartz MJ, Pesce LL, Dellefave-Castillo LM, Vanoye CG, Potet F, Page P, Kearns SD, Pottinger T, White S, Arunkumar P, Olson R, Kofman A, Ibrahim N, Ing A, Brew C, Yap KL, Kadri S, George AL, McNally EM. Genomic autopsy of 103 sudden deaths in the young demonstrates monogenic and oligogenic risk. Journal of the American Medical Association (JAMA) Cardiology, 2021; 6 (11): 1247-1256; doi:10.1001/jamacardio.2021.2789.

Multan M, Alakija P, Orde M, White S. Autopsy education in Canadian pathology programs: a survey of Canadian trainees. American Journal of Forensic Medicine and Pathology, 2020. Published online 21 January 2021; doi:10.1097/PAF.0000000000000665.

Schoppen ZJ, Balmert LC, White S, Olson R, Arunkumar P, Dellefave-Castillo LM, Puckelwartz MJ, George AL, McNally EM, Webster G. Prevalence of Abnormal Heart Weight after Sudden Death in the Young. Journal of the American Heart Association (JAHA), 2020; 9(18): e015699; doi:10.1161/JAHA.120.015699.

Tan YT, Fritsch MK, White S, Arva NC. Dissecting the conduction system: Is it worthwhile? Pediatric and Developmental Pathology, Nov-Dec 2020; 23 (6)”: 413-423; doi:10.1177/1093526620944756.

Gitto L, Serinelli S, Arunkumar P, White SM. Sudden cardiac deaths in adults with congenital heart disease with structural abnormalities: a retrospective review of cases in the Cook County Medical Examiner’s Office. Journal of Forensic Sciences, 2020; 65 (1): 117-127; doi: 10.1111/1556-4029.14165.

Serinelli S, White S, Arunkumar P, Wang D, Gitto L. The outbreak of fentanyl-related deaths in Cook County, Illinois, between October 2015 and December 2017: a retrospective study and comparison with previous data. Journal of Forensic Sciences, 2019; 64 (6): 1735-1742: doi:10.1111/1556-4029.14114.

Serinelli S, Arunkumar P, White S. Undiagnosed congenital heart defects as a cause of sudden, unexpected death in children. Journal of Forensic Sciences, 2018; 63 (6): 1750-1755; doi:10.1111/1556-4029.13779.

Middleton O, Atherton D, Bundock E, Donner E, Friedman D, Hesdorffer D, Jarrell H, McCrillis A, Meno O, Morey M, Thurman D, Tian N, Tomson T, Tseng Z, White S, Wright C, Devinsky O. National Association of Medical Examiners position paper: Recommendations for the investigation and certification of deaths in people with epilepsy. Academic Forensic Pathology. 2018; 8(1): 119-135; doi:10.23907/2018.009.

Middleton O, Atherton D, Bundock E, Donner E, Friedman D, Hesdorffer D, Jarrell H, McCrillis A, Meno O, Morey M, Thurman D, Tian N, Tomson T, Tseng Z, White S, Wright C, Devinsky O. National Association of Medical Examiners position paper: Recommendations for the investigation and certification of deaths in people with epilepsy. Epilepsia. 2018; 59(3): 530-543; doi:10.1111/epi.14030.

Shanks GW, Tester DJ, Ackerman JP, Simpson MA, Behr ER, White SM, Ackerman MJ. Importance of Variant Interpretation in Whole-Exome Molecular Autopsy: A Population-Based Case Series. Circulation. 2018; 137(25): 2705-2715; doi:10.1161/CIRCULATIONAHA.117.031053.

Zhang S, DeBerge M, Yeap XY, Naresh NK, Wang K, Jiang Z, Broussard J, Misener S, White SM, Burridge P, Green KJ, Procissi D, Scott EA, Frazier W, Thorp EB. Acute CD47 Blockade during Ischemic Myocardial Reperfusion Enhances Phagocytosis-Associated Cardiac Repair. Journal of the American College of Cardiology (JACC): Basic to Translational Science. 2017; 2(4): 386-397; doi:10.1016/j.jacbts.2017.03.013.

Cameron S, White SM, Arrollo D, Shulman S, Rowley AH. Arterial Immune Protein Expression Demonstrates the Complexity of Immune Responses in Kawasaki Disease Arteritis. Clinical and Experimental Immunology. 2017; 190 (2): 244-250; doi:10.1111/cei.13010.

Hashem SI, Lam ML, Mihardja SS, White SM, Lee RJ, Claycomb WC. Shox2 Regulates the Pacemaker Gene Program in Embryoid Bodies. Stem Cells and Development 2013; 22(21):2915-26; doi:10.1089/scd.2013.0123.

White SM and Claycomb WC. Embryonic stem cells form and organized, functional cardiac conduction system in vitro. American Journal of Physiology – Heart and Circulatory Physiology. 2005; 288(2): H670-697; doi:10.1152/ajpheart.00841.2004.

Collier JJ, White SM, and Scott DK. The phosphatidylinositol 3-kinase inhibitor LY294002 enhances glucose-stimulated insulin secretion and action potential duration independently of voltage-gated calcium influx in INS-1-derived 832/13 cells. Biochemical and Biophysical Research Communications. 2004; 324: 1018-1023; doi:10.1016/j.bbrc.2004.09.149.

Tracy RE and White SM. A method for quantifying adrenocortical nodular hyperplasia at autopsy. Some use of the method in illuminating hypertension and atherosclerosis. Annals of Diagnostic Pathology. 2002; 6: 20-29; doi:10.1053/adpa.2002.30606.

White SM, Imig JD, Kim TT, Hauschild BC, Inscho EW. Calcium signaling pathways utilized by P2X receptors in freshly isolated preglomerular microvascular smooth muscle cells. American Journal of Physiology-Renal. 2001; 280: F1054-1061; doi:10.1152/ajprenal.2001.280.6.F1054.