Venkata Duvvuri

Not currently accepting graduate research students.

Dr. Duvvuri leads an interdisciplinary research program advancing genomic surveillance research, development, and practice.

His research, broadly termed “AI in Public Health Microbiology,” focuses on:

1. Data Science, AI, and Machine Learning (ML): to incorporate data science and ML into public health microbiology and genomics to develop disease transmission, track AMR, and risk discovery, assessment, and prediction models.
2. Applied Genomic Epidemiology: Combined genomic and epidemiological methods (phylodynamics) to study epidemic potential and disease transmission and evaluate intervention programs.
3. Immuno-informatics: to identify biomarkers from pathogen genomes to develop novel and rapid molecular diagnostic tests and vaccines. 

Selected publications

Duvvuri VR, Baumgartner A, Molani S, et al. Angiotensin-Converting Enzyme (ACE) Inhibitors May Moderate COVID-19 Hyperinflammatory Response: An Observational Study with Deep Immunophenotyping. Health Data Sci.2022;2022:Article 0002

Su Y, Yuan D, Chen DG, Ng RH, Wang K, Choi J, Li S, Hong S, Zhang R, Xie J, Kornilov SA, Scherler K, Pavlovitch-Bedzyk AJ, Dong S, Lausted C, Lee I, Fallen S, Dai CL, Baloni P, Smith B, Duvvuri VR et al. Multiple early factors anticipate post-acute COVID-19 sequelae. Cell. 2022 Mar 3;185(5):881-895.e20. 

Lee JW, Su Y, Baloni P, Chen D, Pavlovitch-Bedzyk AJ, Yuan D, Duvvuri VR, et al. Integrated analysis of plasma and single immune cells uncovers metabolic changes in individuals with COVID-19. Nat Biotechnol. 2022;40(1):110-20.

Su Y, Chen D, Yuan D, Lausted C, Choi J, Dai CL, Voillet V, Duvvuri VR, et al. Multi-omics resolves a sharp disease-state shift between mild and moderate COVID-19. Cell. 2020;183(6):1479-95.e20.

Hicks JT, Lee D-H, Duvvuri VR, et al. Agricultural and geographic factors shaped the North American 2015 highly pathogenic avian influenza H5N2 outbreak. PLoS Pathog. 2020;16(1):e1007857.

Duvvuri VR, Deng X, Teatero S, et al. Population structure and drug resistance patterns of emerging non-PCV-13 Streptococcus pneumoniae serotypes 22F, 15A, and 8 isolated from adults in Ontario, Canada. Infect Genet Evol. 2016;42:1-8.

Duvvuri VR, Granados A, Rosenfeld P, Bahl J, Eshaghi A, Gubbay JB. Genetic diversity and evolutionary insights of respiratory syncytial virus A ON1 genotype: global and local transmission dynamics. Sci Rep. 2015;5:14268.

A. Eshaghi, VR. Duvvuri, R et al. Genetic variability of human respiratory syncytial virus a strains circulating in ontario: a novel genotype with a 72 nucleotide G gene duplication. PLoS One. 2012;7(3):e32807