B. Lowell Langille Vascular Biology Lectureship: Molecular drivers of endothelial and epithelial tubulogenesis
As part of our Monday seminar series, we are delighted to welcome our speaker:
Ondine Cleaver, PhD
Professor
Molecular Biology
UT Southwestern Medical Center
Dallas Texas
Hosted by
Jason Fish, PhD
How to join
An email including Zoom link will be sent to the LMP community.
If you are not part of LMP and wish to join, please contact:
Louella D'Cunha
Speaker: Ondine Cleaver
Dr. Cleaver was born in Palo Alto, California and grew up near Montreal, in Quebec, Canada.
She received her B.S. in Molecular Biology and B.A. in History from UT Austin. She also earned her graduate degree at UT Austin, focusing on the role of VEGF and VEGFR2 on endothelial progenitor patterning with Dr. Paul Krieg. She performed her postgraduate research at Harvard, in the Department of Cellular and Molecular Biology with Dr. Douglas Melton. She identified vascular signals important during specification of pancreatic beta cells.
Dr. Cleaver joined UT Southwestern’s Molecular Biology as faculty in late 2004 and was promoted to Associate Professor in 2010. In 2016, she was promoted to full Professor. She is Chair of the UTSW Genetics, Development and Disease graduate program. She has been SDB Secretary and Board member for the past 3 years. She was a member of the NIH Cardiovascular Differentiation and Development study section from 2014-2019 and president of the North American Vascular Biology Organization (NAVBO) 2019-2020. She is currently an organizer of the Angiogenesis GRC 2023.
Her lab studies cell fate and how cells assemble into functional tissues.
Her group is particularly interested in intracellular signaling events that drive cytoskeletal or adhesion changes within progenitor cells. Regulation of these structural components modulate cell shape, cell-cell interactions and cell differentiation that coordinate during tissue morphogenesis. Her lab has focused on blood vessels and on developing organs, such as the pancreas, the kidney, and the lung. She is interested in how cues in the microenvironment drive vascular assembly or growth, and how blood vessels in turn communicate paracrine, non-nutritional signals to stem cell niches.