Professor Emeritus

Kalman Kovacs

Department of Laboratory Medicine & Pathobiology


St. Michael’s Hospital: Unity Health Toronto
30 Bond St. Room 2-101V, Toronto, Ontario Canada M5B 1W8
Research Interests
Brain & Neuroscience, Cancer
Appointment Status

Research Synopsis

Dr Kovacs' research studies pituitary tumours using histology, immunohistochemistry, electron microscopy and, in collaboration, applying molecular/genetic methods.

Tumour morphology is correlated with clinical findings, endocrinologic and imaging parameters.

Investigations include:

  • biomarkers
  • angiogenesis
  • biologic behaviour
  • prediction of prognosis
  • assessment of therapeutic responsiveness.


Recent Publications


Horvath E, Kovacs K. Histopathology of pituitary tumors. In:Oxford Textbook of Endocrinology and Diabetes. Second  edition. Eds. Wass JAH and Steward PM, Oxford University  Press, p.121-127, 2011.

Moshkin O, Rotondo F, Scheithauer BW, Soares M, Coire C, Smyth HS, Goth M, Horvath E, Kovacs K. Bronchial carcinoid tumors metastatic to the sella turcica and review of the literature. Pituitary 15:160-165, 2012.

Rotondo F, Rotondo A, Scheithauer BW, cusimano M, Latta E, Syro LV, Kovacs K. Ghrelin immunoexpression in the human hypophysis. Appl Immunohistochem Mol Morphol 20:77-81, 2012

Rotondo F, Cusimano M, Scheithauer BW, Rotondo A, Syro SL, Kovacs K. Ghrelin immunoexpression in pituitary adenomas. Pituitary,14:318-322, 2011.

Sivapragasam M, Rotondo f, Lloyd RV, Scheithauer BW,  Cusimano M, Syro LV, Kovacs K. MicroRNAs in the human pituitary. Endocri Pathol 22:134-143, 2011.

Nassiri F, Cusimano MD, Scheithauer BW, Rotondo F, Fazio A, Yousef GM, Syro LV, Kovacs K, Lloyd RV. Endoglin (CD105): a review of its role in angiogenesis and tumor diagnosis, progression and therapy. Anticancer Res 31:2283-2290, 2011.