Assistant Professor

Shachar Sade

Department of Laboratory Medicine & Pathobiology - Anatomic Pathology


Sunnybrook Health Science Centre
2075 Bayview Ave., Department of Anatomical Pathology, Toronto, Ontario Canada M4N 3M5
Research Interests
Clinical Interests
Pathology: Dermatopathology, Pathology: Anatomical
Appointment Status

Professional Memberships

  • Member, Odette Cancer Centre Melanoma Council

Dr Sade received his medical degree (MD) from Western University and completed his anatomical pathology residency training at McMaster University and McGill University (FRCPC) as well as a research-based Masters degree (MSc) and clinical fellowship training in Dermatopathology at the Univeristy of Toronto. 

Dr Sade is an academic dermatopathologist at Sunnybrook Health Sciences Centre with cross appointments at Women's College Hospital and University Health Network, and is a member of the Odette Cancer Centre Melanoma Council. 

He has a keen interest in post-graduate medical education and is the current Program Director for Anatomical Pathology at the University of Toronto.


Research Synopsis


My research interests include melanocytic lesions, epidermal tumours and cutaneous lymphomas, and I am actively engaged in consultation work and collaborative clinical research in these fields.


Recent Publications


Pyoderma gangrenosum secondary to azacitidine in myelodysplastic syndrome. Tseng E, Alhusayen R, Sade S, Buckstein R, Prica A. Br J Haematol. 2015 May;169(4):461. doi: 10.1111/bjh.13341. Epub 2015 Mar 12. PMID: 25765235

Erratum to: Pathologic Complete Response to Intralesional Interleukin-2 Therapy Associated with Improved Survival in Melanoma Patients with In-Transit Disease. Hassan S, Petrella TM, Zhang T, Kamel-Reid S, Nordio F, Baccarelli A, Sade S, Naert K, Al Habeeb A, Ghazarian D, Wright FC. Ann Surg Oncol. 2014 Dec 12. [Epub ahead of print] PMID: 25503348

Pathologic complete response to intralesional interleukin-2 therapy associated with improved survival in melanoma patients with in-transit disease.Hassan S, Petrella TM, Zhang T, Kamel-Reid S, Nordio F, Baccarelli A, Sade S, Naert K, Habeeb AA, Ghazarian D, Wright FC. Ann Surg Oncol. 2015 Jun;22(6):1950-8. doi: 10.1245/s10434-014-4199-z. Epub 2014 Nov 1. PMID: 25366584

Vasculotide, an Angiopoietin-1 mimetic, reduces acute skin ionizing radiation damage in a preclinical mouse model. Korpela E, Yohan D, Chin LC, Kim A, Huang X, Sade S, Van Slyke P, Dumont DJ, Liu SK. BMC Cancer. 2014 Aug 26;14:614. doi: 10.1186/1471-2407-14-614. PMID: 25159192

How often do level III nodes bear melanoma metastases and does it affect patient outcomes?  Nessim C,  Law C, McConnell Y, S Shachar, McKinonn G, Wright F. Ann Surg Oncol. 2013 Jun; 20(6):2056-64.

Florid cutaneous and mucosal papillomatosis: mucocutaneous markers of an underlying gastric malignancy. Klieb HB, Avon SL, Gilbert J, Sade S, Enepekides D. J Clin Oncol. 2013 May 1;31(13):e218-9. doi: 10.1200/JCO.2012.45.2151. Epub 2013 Mar 25. PMID: 23530104

Syringocystadenocarcinoma papilliferum in situ of the penis. Plant MA, Sade S, Hong C, Ghazarian DM. Eur J Dermatol. 2012 May-Jun;22(3):405-6. doi: 10.1684/ejd.2012.1723. No abstract available.  PMID: 22510243

Dilemmas in Infectious Disease:  From the oustide looking in.  Moayedi Y, Bunce PE, Sade S, Ghazarian D, Gold WL. Am J Med. 2012 May;125(5):457-60. doi: 10.1016/j.amjmed.2011.10.021. Epub 2012 Feb 22. PMID: 22365025

Oral melanosis after tyrosine kinase inhibition with Imatinib for chronic myelogenous leukemia: report of a case and review of the literature. Wong M, Sade S, Gilbert M, Klieb HB. Dermatol Online J. 2011 May 15;17(5):4. Review. PMID: 21635826

Syringoid eccrine carcinoma: a clinicopathological and immunohistochemical study of four cases. Sidiropoulos M, Sade S, Al-Habeeb A, Ghazarian D. J Clin Pathol. 2011 Sep;64(9):788-92. doi: 10.1136/jclinpath-2011-200069. Epub 2011 Jun 4. PMID: 21642659

Spindle cell melanocytic lesions: part II--an approach to intradermal proliferations and horizontally oriented lesions. Sade S, Al Habeeb A, Ghazarian D. J Clin Pathol. 2010 May;63(5):391-409. doi: 10.1136/jcp.2010.075440. Review. PMID: 20418231

Spindle cell melanocytic lesions--part I: an approach to compound naevoidal pattern lesions with spindle cell morphology and Spitzoid pattern lesions. Sade S, Al Habeeb A, Ghazarian D. J Clin Pathol. 2010 Apr;63(4):296-321. doi: 10.1136/jcp.2009.075226. Review. PMID: 20354202